DNA end resection is crucial for most DNA double-strand break repair pathways. This Review discusses the molecular mechanisms of end resection and its regulation, focusing on the roles of post-translational modifications throughout the cell cycle and in response to DNA damage.
The new test could help identify which patients are most likely to benefit from new Alzheimer’s drugs. A newly developed blood test for Alzheimer’s disease not only helps confirm the presence of the condition but also provides information about how far the disease has progressed, according to resea
Atsena Therapeutics has raised $150 million in an oversubscribed series C financing, with hopes that the funds can carry the biotech’s gene therapy designed to reverse or prevent blindness through a potential market approval.
The funding round was led by new investor Bain Capital, with participation from Sofinnova Investments, Abingworth, Wellington Management, Lightstone Ventures, Foundation Fighting Blindness, Hatteras Venture Partners, Osage University Partners and the Manning Family Foundation, according to an April 2 release.
Discover groundbreaking advancements in Alzheimer’s research, focusing on secretory dysfunction and innovative therapeutic approaches.
Could Short Chains of Amino Acids Revolutionize Anti-aging? We explore the exciting potential of peptide therapy to address key hallmarks of aging, including biological age and telomere length. This video delves into the science behind peptides and examines early clinical findings that suggest significant possibilities for age reversal.
What you’ll learn:
• Key peptides being studied for anti-aging (Epitalon, GHK-Cu, etc.).
• A look at clinical studies and patient data.
• The future of peptide therapy in longevity research.
Credits to : glycanage, dr. luis martinez of clinical peptide society
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When your social media account starts spewing out nonsensical or threatening status updates, it’s safe to assume that it has been hacked and must be shut down.
The cells in our body also update their “status” by presenting to their environment small proteins that are constantly being produced inside the cell. Our immune system monitors these statuses and destroys cells that produce unusual proteins. A classic example of this is when a cell is infected by a virus and presents parts of the viral proteins on its surface, which allows the immune system to recognize them and destroy the cell.
In contrast, cancer cells often evade detection by displaying very few suspicious proteins that the immune system can identify and target. A new approach to cancer treatment, developed by researchers from Prof. Yardena Samuels’s lab at the Weizmann Institute of Science, increases the number of the immune system’s targets by disrupting protein production in cancerous cells.
(https://twitter.com/neuralink/status/1907493477086117955)
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At the viral chatter stage of an outbreak, pathogens are just starting to infect people in sporadic bursts. It’s a sign that a pandemic may be on the horizon.
Large-scale analyses of electronic health data suggest that the herpes zoster vaccine could protect against dementia — but it’s not yet clear how.
