Lifeboat Foundation

It’s available on phones and now watches? That’s actually nice though I hope they make it battery efficient. The Pixel watch for example already has issues with battery life. I’m the future will there be a small AI server in our bodies in microchips or a network of nanobots?

ChatGPT is all the rage these days, but did you know you can get it on your watch? Here’s how to install it on a Galaxy Watch, Pixel Watch, and other Wear OS watches.

The nanoscale electronic parts in devices like smartphones are solid, static objects that once designed and built cannot transform into anything else. But University of California, Irvine physicists have reported the discovery of nanoscale devices that can transform into many different shapes and sizes even though they exist in solid states.

It’s a finding that could fundamentally change the nature of electronic devices, as well as the way scientists research atomic-scale quantum materials. The study is published in Science Advances.

“What we discovered is that for a particular set of materials, you can make nanoscale electronic devices that aren’t stuck together,” said Javier Sanchez-Yamagishi, an assistant professor of physics & astronomy whose lab performed the new research. “The parts can move, and so that allows us to modify the size and shape of a device after it’s been made.”

This new “nano-excitonic transistor” could revolutionize data processing, especially in the age of AI.

The Singularity is a technological event horizon beyond which we cannot see – a moment in future history when exponential progress makes the impossible possible. This video discusses the concept of the Singularity, related technologies including AI, synthetic biology, cybernetics and quantum computing, and their potential implications.

My previous video “AI, Robots & the Future” is here:
https://www.youtube.com/watch?v=iaGIo_Viazs.

Continue reading “Explaining the Singularity” »

Proteins are involved in every biological process, and use the energy in the body to alter their structure via mechanical movements. They are considered biological ‘nanomachines’ because the smallest structural change in a protein has a significant effect on biological processes. The development of nanomachines that mimic proteins has received much attention to implement movement in the cellular environment. However, there are various mechanisms by which cells attempt to protect themselves from the action of these nanomachines. This limits the realization of any relevant mechanical movement of nanomachines that could be applied for medical purposes.

The research team led by Dr. Youngdo Jeong from the Center for Advanced Biomolecular Recognition at the Korea Institute of Science and Technology (KIST, President Seok-Jin Yoon) has reported the development of a novel biochemical nanomachine that penetrates the cell membrane and kills the cell via the molecular movements of folding and unfolding in specific cellular environments, such as cancer cells, as a result of a collaboration with the teams of Prof. Sang Kyu Kwak from the School of Energy and Chemical Engineering and Prof. Ja-Hyoung Ryu from the Department of Chemistry at the Ulsan National Institute of Science and Technology (UNIST, President Yong Hoon Lee), and Dr. Chaekyu Kim of Fusion Biotechnology, Inc.

The joint research team focused on the hierarchical structure of proteins, in which the axis of the large structure and the mobile units are hierarchically separated. Therefore, only specific parts can move around the axis. Most existing nanomachines have been designed so that the mobile components and axis of the large structure are present on the same layer. Thus, these components undergo simultaneous movement, which complicates the desired control of a specific part.

Called the nanofluidic drug-eluting seed (NDES), it delivers low-dose immunotherapy in the form of CD40 monoclonal antibodies (mAb).

In a significant groundbreaking medical development, researchers have created a tiny device, smaller than a grain of rice, to deliver drugs directly to the pancreatic tumor.

Nano-device uses less dosage to shrink cancer.

Continue reading “Novel device smaller than rice successfully shrinks pancreatic cancer” »

Scientists have discovered yet another amazing aspect of the weird and wonderful behavior of water—this time when subjected to nanoscale confinement at sub-zero temperatures.

The finding that a crystalline substance can readily give up water at temperatures as low as −70 °C, published in the journal Nature on April 12, has major implications for the development of materials designed to extract water from the atmosphere.

Continue reading “Scientists identify new benchmark for freezing point of water at —70 C” »

Promising results in clinical studies have been demonstrated by the utilization of electrothermal agents (ETAs) in cancer therapy. However, a difficulty arises from the balance between facilitating the degradation of ETAs, and at the same time, increasing the electrothermal performance/stability required for highly efficient treatment. In this study, we controlled the thermal signature of the MoS2 by harnessing MoS2 nanostructures with M13 phage (MNM) via the structural assembling (hydrophobic interaction) phenomena and developed a combined PANC-1 cancer cell–MNM alternating current (AC)-stimulus framework for cancer cell ablation and electrothermal therapy. A percentage decrease in the cell viability of ~23% was achieved, as well as a degradation time of 2 weeks; a stimulus length of 100 μs was also achieved.

The remarkable physicochemical properties of the natural nucleic acids, DNA and RNA, define modern biology at the molecular level and are widely believed to have been central to life’s origins. However, their ability to form repositories of information as well as functional structures such as ligands (aptamers) and catalysts (ribozymes/DNAzymes) is not unique. A range of nonnatural alternatives, collectively termed xeno nucleic acids (XNAs), are also capable of supporting genetic information storage and propagation as well as evolution. This gives rise to a new field of “synthetic genetics,” which seeks to expand the nucleic acid chemical toolbox for applications in both biotechnology and molecular medicine. In this review, we outline XNA polymerase and reverse transcriptase engineering as a key enabling technology and summarize the application of “synthetic genetics” to the development of aptamers, enzymes, and nanostructures.

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