Archive for the ‘life extension’ category: Page 592
Jul 12, 2016
Blood of world’s oldest woman hints at limits of life
Posted by Montie Adkins in categories: biotech/medical, life extension
This is from 2014 but is getting posted around the past couple of days.
““It’s estimated that we’re born with around 20,000 blood stem cells, and at any one time, around 1000 are simultaneously active to replenish blood,” says Holstege. During life, the number of active stem cells shrinks, she says, and their telomeres shorten to the point at which they die –”
She lived to 115, but a study of Hendrikje van Andel-Schipper’s blood hints at factors limiting lifespan.
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Jul 11, 2016
How To Become Immortal — By The People Who Think You Can
Posted by Genevieve Klien in categories: biotech/medical, life extension
Amazing!! More time to learn, evolve, love, & explore the world…
A sprawling facility called Timeship in Texas will host 50,000 frozen dead people with one goal — to become the human race’s first immortals.
Activist Saul Kent — one of the minds behind it — is such a passionate believer in ‘cryogenics’ that he froze his own mother’s head in 1988 after her death.
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Jul 11, 2016
Pomegranate finally reveals its powerful anti-aging secret
Posted by Bruno Henrique de Souza in categories: biotech/medical, health, life extension
Are pomegranates really the superfood we’ve been led to believe will counteract the aging process? Up to now, scientific proof has been fairly weak. And some controversial marketing tactics have led to skepticism as well. A team of scientists from EPFL and the company Amazentis wanted to explore the issue by taking a closer look at the secrets of this plump pink fruit. They discovered that a molecule in pomegranates, transformed by microbes in the gut, enables muscle cells to protect themselves against one of the major causes of aging. In nematodes and rodents, the effect is nothing short of amazing. Human clinical trials are currently underway, but these initial findings have already been published in the journal Nature Medicine.
As we age, our cells increasingly struggle to recycle their powerhouses. Called mitochondria, these inner compartments are no longer able to carry out their vital function, thus accumulate in the cell. This degradation affects the health of many tissues, including muscles, which gradually weaken over the years. A buildup of dysfunctional mitochondria is also suspected of playing a role in other diseases of aging, such as Parkinson’s disease.
One molecule plays David against the Goliath of aging
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Jul 8, 2016
The Role of Mitochondria in Metastatic Cancer
Posted by Karen Hurst in categories: biotech/medical, life extension
For all my Precision Medicine, Cancer researchers, and anti-aging friends researchers have id that the mitochondria pathway has been used by cancer cells to exploit for motility and metastasis.
Researchers have identified a new mitochondrial pathway that cancer cells exploit for motility and metastasis—providing a viable, “druggable” target for many different types of tumors. [NIEHS].
Are you an avid supporter of aging research and a keen longevity activist?
The Biogerontology Research Foundation is offering select summer internships for talented individuals. You’d join a passionate and supportive team in researching diagnostic, prognostic, and therapeutic strategies; advising a panel of investors in developing a roadmap to promote longevity science and related technologies across the globe.
The advertised positions are 3 month internships, with the possibility of continuing afterwards. Free accommodation will be provided for in London, alongside a negotiable salary.
The Biogerontology Research Foundation is a UK based think tank dedicated to aging research and accelerating its application worldwide.
Jul 4, 2016
OncoSENS Control ALT Delete Cancer
Posted by Steve Hill in categories: biotech/medical, life extension
Happy 4th of July! Time for our own independence day from cancer!
High-throughput screening of a library of diverse drugs to find treatments for ‘ALT’ cancers, those which rely on Alternative Lengthening of Telomeres.
Jul 4, 2016
Stopping Cancer at the Starting Line
Posted by Steve Hill in categories: biotech/medical, life extension
Narrated by actor Edward James Olmos, this video describes one of the body’s critical anti-cancer defences – the telomeres. These caps on the ends of our chromosomes shorten each time a cell divides and, when they become too short, trigger the cell to self-destruct. When a cell grows too rapidly, it and all of its descendants normally suffer this fate. Such growths are sometimes called “pre-cancer”. Since our stem cells need to be able to divide without this constraint in order to replace cells lost across the body, they produce the enzyme telomerase to re-extend their telomeres. Unfortunately, a small number of pre-cancerous cells manage to activate their own copies of the telomerase gene, escaping the limit on their growth. SENS Research Foundation is developing therapies to completely block telomere extension in pre-cancerous cells, ensuring the body’s existing defences can function as intended.
Jun 28, 2016
The Top Ten Reasons I Believe Vaccine Safety Is an Epic Mass Delusion
Posted by Eric Baum in categories: biotech/medical, ethics, existential risks, government, health, life extension, policy, rants, science, scientific freedom
Its painful to bear views that make many think I’m an imbicile and dislike me. So please, if anybody has a rational argument why any of this is wrong, I beg to be enlightened. I’ve set up a diagram for the purpose that will support you to add your criticism exactly where it is pertinent. https://tssciencecollaboration.com/graphtree/Are%20Vaccines%20Safe/406/4083
(1) The National Academy’s Reviews Of Vaccine Safety
The Institute of Medicine of the National Academies has provided several multi-hundred page surveys studying the safety of vaccines, but rather than reassuring, these itemize some iatrogenic conditions being caused, and pronounce the scientific literature inadequate to say whether most others are. The 2011 Institute of Medicine (IOM) Review[1] looked at 146 vaccine-condition pairs for causality, reporting:
- 14 for which the evidence is said to convincingly support causality, the vaccine is causing the condition.
- 4 where the evidence is said to favor acceptance.
- 5 where the evidence is said to favor rejection, including MMR causing autism.
- 123 where the evidence is said insufficient to evaluate.
The 2003 IOM Review on multiple vaccines said[2]:
“The committee was unable to address the concern that repeated exposure of a susceptible child to multiple immunizations over the developmental period may also produce atypical or non-specific immune or nervous system injury that could lead to severe disability or death (Fisher, 2001). There are no epidemiological studies that address this.”
and:
“the committee concludes that the epidemiological and clinical evidence is inadequate to accept or reject a causal relationship between multiple immunization and an increased risk of allergic disease, particularly asthma.”
- None of the IOM Safety Reviews[1][2][3][4] addressed the aluminum (for example whether the aluminum is causing autism), or mentioned contaminants, or discussed animal models although they had concluded as just quoted there is generally no epidemiological or clinical data worth preferring.
(2) The Aluminum.
Alum was added to vaccines back in the 1920’s, with no test of parenteral toxicity until recently[5], because it prods the immature immune system out of its normal operating range.[6] Maybe they figured aluminum is common in the environment, but injection bypasses half a dozen evolved sequential filters that normally keep it out of circulatory flow during development. Vaccines put hundreds of times as much aluminum into infants’ blood as they would otherwise get, and in an unnatural form that is hard for the body to remove.[7][8 (cfsec 4.2)][9]. The published empirical results indicate its highly toxic.
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Jun 28, 2016
Pre and post testing show reversal of memory loss from Alzheimer’s disease in 10 patients
Posted by Alexandros El in categories: biotech/medical, chemistry, employment, health, life extension, neuroscience
Results from quantitative MRI and neuropsychological testing show unprecedented improvements in ten patients with early Alzheimer’s disease (AD) or its precursors following treatment with a programmatic and personalized therapy. Results from an approach dubbed metabolic enhancement for neurodegeneration are now available online in the journal Aging.
The study, which comes jointly from the Buck Institute for Research on Aging and the UCLA Easton Laboratories for Neurodegenerative Disease Research, is the first to objectively show that memory loss in patients can be reversed, and improvement sustained, using a complex, 36-point therapeutic personalized program that involves comprehensive changes in diet, brain stimulation, exercise, optimization of sleep, specific pharmaceuticals and vitamins, and multiple additional steps that affect brain chemistry.
“All of these patients had either well-defined mild cognitive impairment (MCI), subjective cognitive impairment (SCI) or had been diagnosed with AD before beginning the program,” said author Dale Bredesen, MD, a professor at the Buck Institute and professor at the Easton Laboratories for Neurodegenerative Disease Research at UCLA, who noted that patients who had had to discontinue work were able to return to work and those struggling at their jobs were able to improve their performance. “Follow up testing showed some of the patients going from abnormal to normal.”