Lifeboat Foundation

A new finding in experiments studying the dry preservation of living cells — a potentially revolutionary alternative to cryopreservation — has defined a clear limit where continuing dehydration kills cells. The data, combined with molecular dynamics simulations, provides insight into an important processing factor that has limited recent attempts at dry preservation.

“What we have done is identified what appears to be a materials constraint in our method of dry preservation. I think this new understanding suggests some interesting avenues to pursue in developing a successful process,” said Gloria Elliott, Professor of Mechanical Engineering at the University of North Carolina at Charlotte, one of the study’s authors.

The findings, reported in the July 8 issue of Scientific Reports, analyzes changes in the molecular arrangements of trehalose (a sugar) and water molecules during a typical dehydration process that they use to immobilize cells in a stable trehalose glass for long-term storage.

Continue reading “Study shows continuous dehydration kills cells during dry preservation” »

SENS has a fund match for its current campaign on lifespan.io, if you are concerned about cancer like me and you want to help directly fund a lab working on solutions please think about donating. smile

There is a month left to go in the SENS crowdfunding campaign that aims to accelerate development of an important component of a universal cancer therapy, a way to block the mechanisms of telomere lengthening that every type of cancer depends upon. The SENS Research Foundation and Lifespan.io volunteers are looking for donors to put up matching funds of a few thousand dollars or more, in order to take that news and that inducement to a number of conferences and other events over the next few weeks. More than 150 people have donated to the campaign to date, and we’d like to triple that number in the next 30 days.

To start things off, I’ll offer up $2,000 of my own funds: the next $2,000 in donations to this SENS cancer research initiative will be matched dollar for dollar. That is a start, and if you can join in to help out, please contact me to let me know. Can you help to make a difference here?

Continue reading “Matching Fund Donors Sought for SENS Universal Cancer Therapy Crowdfunding” »

Researchers at the Stanford University School of Medicine found a way to trick human embryonic stem cells to become pure populations of any of 12 cell types, including bone, heart muscle and cartilage within days.

Scientists at the Stanford University School of Medicine have identified the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells. If successful, researchers could grow pure populations of any of 12 cell types, including bone, heart muscle and cartilage within days rather than the weeks or months previously required.

This is key toward clinically useful regenerative medicine – potentially allowing researchers to generate new beating heart cells to repair damage after a heart attack or to create cartilage or bone to reinvigorate creaky joints or heal from trauma.

Continue reading “Stanford Researchers ‘Trick’ Human Stem Cells To Regenerate Faster” »

https://youtube.com/watch?v=VlGADx1s1zQ

It’s not just religious terrorism that is killing people. A religious anti-science culture—which most of us live amongst—also cuts short everyone’s lives. People simply don’t care much about longevity if they believe in an afterlife.

All around the world, religious terror is striking and threatening us. Whether in France, Istanbul, London, or the USA, the threat is now constant. We can fight it all we want. We can send out our troops; we can chip refugees; we can try to monitor terrorist’s every move. We can even improve trauma medicine to deal with extreme violence they bring us. But none of this solves the underlying issue: Abrahamic religions like Christianity and Islam are fundamentally violent philosophies with violent Gods. Sam Harris, Richard Dawkins, Christopher Hitchens and others have all reiterated essentially the same thing.

Continue reading “Atheist Presidential Candidate: Religion is Literally Killing Us” »

Transhumanists will know that the science fiction author Zoltan Istvan has unilaterally leveraged the movement into a political party contesting the 2016 US presidential election. To be sure, many transhumanists have contested Istvan’s own legitimacy, but there is no denying that he has generated enormous publicity for many key transhumanist ideas. Interestingly, his lead idea is that the state should do everything possible to uphold people’s right to live forever. Of course, he means to live forever in a healthy state, fit of mind and body. Istvan cleverly couches this policy as simply an extension of what voters already expect from medical research and welfare provision. And while he may be correct, the policy is fraught with hazards – especially if, as many transhumanists believe, we are on the verge of revealing the secrets to biological immortality.

In June, Istvan and I debated this matter at Brain Bar Budapest. Let me say, for the record, that I think that we are sufficiently close to this prospect that it is not too early to discuss its political and economic implications.

Two months before my encounter with Istvan, I was on a panel at the Edinburgh Science Festival with the great theorist of radical life extension Aubrey de Grey, where he declared that people who live indefinitely will seem like renovated vintage cars. Whatever else, he is suggesting that they would be frozen in time. He may actually be right about this. But is such a state desirable, given that throughout history radical change has been facilitated generational change? Specifically, two simple facts make the young open to doing things differently: The young have no memory of past practices working to anyone else’s benefit, and they have not had the time to invest in those practices to reap their benefits. Whatever good is to be found in the past is hearsay, as far as the young are concerned, which they are being asked to trust as they enter a world that they know is bound to change.

Questions have been already raised about whether tomorrow’s Methuselahs will wish to procreate at all, given the time available to them to realize dreams that in the past would have been transferred to their offspring. After all, as human life expectancy has increased 50% over the past century, the birth rate has correspondingly dropped. One can only imagine what will happen once ageing can be arrested, if not outright reversed!

Continue reading “Beware the Rise of Gerontocracy: Some Hard Lessons for Transhumanism, Not Least from Brexit” »

Transhuman Terminology.

ADHOCRACY
AEONOMICS
A-LIFE
AGORIC SYSTEM

AI-COMPLETE ALEPH ALGERNON AMORTALIST ARACHNIOGRAPHY ARCH-ANARCHY ARCOLOGY ARROW IMPOSSIBILITY THEOREM ARTILECT ASEX ASIMORT ASIMOV ASSEMBLER ATHANASIA ATHANOPHY ATHEOSIS AUGMENT AUTOEVOLUTIONIST AUTOMATED ENGINEERING AUTOMORPHISM AUTOPOTENT AUTOSCIENT BABY UNIVERSE BASEMENT UNIVERSE BEAN DIP CATASTROPHE BEANSTALK BEKENSTEIN BOUND BERSERKER BETELGEUSE-BRAIN BIG CRUNCH BINERATOR BIOCHAUVINISM BIOLOGICAL FUNDAMENTALISM BIONICS BIONOMICS BIOPHILIAC BIOSTASIS B-LIFE BLIGHT BLIND UPLOADING BLUE GOO BOGOSITY FILTER BORGANISM BREAKEVEN POINT BROADCATCHING BRUTE FORCE UPLOADING BUSH ROBOT CALCUTTA SYNDROME CALM TECHNOLOGY CALORIE RESTRICTION CASIMIR EFFECT CEREBROSTHESIS CHINESE ROOM CHRONONAUTS CHURCH-TURING THESIS COBOTS COMPUFORM COMPUTRONIUM CONCENTRATED INTELLIGENCE CONSILIENCE CONNECTIONISM CONTELLIGENCE CONTINUITY IDENTITY THEORY COSMYTHOLOGY CRYOBIOLOGY CRYOCRASTINATE CRYOGENICS CRYONICS CRYONIC SUSPENSION CRYPTO ANARCHY CRYPTOCOSMOLOGY CYBERCIDE CYBERFICTION CYBERGNOSTICISM CYBERIAN CYBERNATE/CYBERNIZE CYBERSPACE/CYBERMATRIX CYBRARIAN CYPHERPUNK DEANIMALIZE DEATH FORWARD DEATHISM DEEP ANARCHY DEFLESH DIGITAL PSEUDONYM DIAMONDOID DISASSEMBLER DISASTERBATION DISTRIBUTED INTELLIGENCE DIVERGENT TRACK HYPOTHESIS DIVERSITY IQ DIVIDUALS DOOMSDAY ARGUMENT DOWNLOAD DRYWARE DUBIFIER DYSON SPHERE ECOCALYPSE ECTOGENESIS

EMBRYOMEME
EMULATION
ENHANCED REALITY
ENVIROCAPITALISM
EPHEMERALISTS
E-PRIME
ESCALATORLOGY
THE ETERNAL LIFE POSTULATE
EUPSYCHIA
EUTHENICS
EVOLUTIONARILY STABLE STRATEGY (ESS)
EVOLUTURE
EXCONOMICS
EXES
EXFORMATION
EXISTENTIAL TECHNOLOGY
EXOPHOBIA
EXOSELF
EXTROPIAN
EXTROPIATE
EXTROPIC
EXTROPOLIS
EXTROPY
FACULTATIVE ANAGOROBE
FAR EDGE PARTY
THE FERMI PARADOX
FEMTOTECHNOLOGY
FLATLANDER
FLUIDENTITY
FOGLET
FORK
FREDKIN’S PARADOX
FUNCTIONAL SOUP
FUTIQUE
FUTURE SHOCK
GALAXY BRAIN
GAUSSIAN
GENEGENEERING
GENETIC ALGORITHM
GENIE
GREEN GOO
GÖDEL’S THEOREM
GOLDEN GOO
GREAT FILTER, THE
GREY GOO
GUY FAWKES SCENARIO
HALLUCINOMEMIC
HIVE COMPUTING
HOMORPH
HPLD
HYPERTEXT
HYPONEIRIA
HYPOTECH

Continue reading “Transhumanist Terminology” »

If you are interested in the work of SENS and how Dr Haroldo Silva and his team are looking for ways to treat cancer why not come along and join them?

There is going to be a SENS AMA on Reddit with Aubrey de Grey and OncoSENS researcher Haroldo Silva. Ask them anything about SENS and the long term goal of developing universal cancer therapies.

FUTUROLOGY JULY 19TH 1 pm EST/10 am PST/6 pm BST.

Continue reading “Dr Aubrey de Grey is doing an AMA 19th in Reddit Futurology 1pm EST/6pm BST” »

Philosophers have been debating the meaning of life for millennia. Billions of people believe that the principal aim in life is to experience pleasure, and they try to enjoy life as much as possible before they die. A minority of others, make it their life’s aim to achieve something which is over and above simple pleasure: not merely to help others, not even to help humanity at large. They aim, whether knowingly or unknowingly, to improve the evolutionary process of nature as a whole.

So far, so good. But it appears that the view we hold about our life, our worldview, has a direct impact on our biology. We know that thinking positively may help improve the immune system. But research also shows that people who aim for pleasure (Hedonia) may have an impaired genetic profile, compared to those who aim for higher virtues (Eudaimonia). There is a distinction between these two terms and it is worth providing a definition here:

Hedonia is an exclusive search for pleasure and avoidance of discomfort. It may involve increased emphasis on eating well, drinking, dancing, playing, and generally enjoying simple pleasures in life. It is contentment, gratification, fun, merriment, satisfaction and, perhaps necessarily, a lack of motivation to search for a nobler aim in life. One may argue that hedonia involves a risk that leads to bad health due to a tendency to excesses (smoking, alcohol, coffee, sweets), a general inclination to avoid uncomfortable physical activity, and a lack of challenging cognitive effort. The risk of addiction may be increased. Erosion of social bonds become a possibility when a hedonist is more concerned about his/her own pleasure and is less sensitive to the needs of others.

Eudaimonia is a term reflecting the highest ‘intellectual good’. It is virtue plus excellence, superior ethical refinement, cognitive sophistication, as well as other qualities such as persistent motivation, wisdom, imagination, creativity, vision and a feeling of purpose. The term has been discussed by many ancient Greek philosophers particularly Aristotle and the Stoics. In modern times and in a wider sense, eudaimonia may be equated with meaningful technological hyperconnection, or ‘Intentional Evolution’, an attempt to constructively improve the human condition in all respects (including those relating to the wider universe). Hedonia is found both in animals and in humans, whereas eudaimonia is only found in humans.

Continue reading “Is physical pleasure bad for your health?” »

Here’s Liz Parrish talking about driving down costs, replacing viral vectors, and having all kinds of trouble with the lid of a bottle.

Liz Parrish, founder or Bioviva company, which developing genetic therapy against aging. He first in world tested such genetic therapy on himself and resulting effect make her cells be like 20 years younger.

Continue reading “3/3 Liz Parrish and Avi Roy: Genetic and other innovative therapy against aging” »