Lifeboat Foundation

Long vid. Slight annotation in the comments. A few takaways I liked: We need to move to human data instead of mice. People’s attitude towards life extension should change drastically soon. There is human data among this group and have released it, will keep following it, and some to be released soon. Sinclair thinks he can start primate trials this year. And overall everyone is optimistic.

A couple of weeks ago Avi Roy, alongside Nathan Cheng & Laura Minquini, hosted the Longevity Panel discussion, which assembled some of the biggest scientists in the field currently working on reversing aging.

Continue reading “Longevity Panel — The Scientists working on Reversing Aging | Part 1” »

Researchers and entrepreneurs are starting to ponder how AI could create versions of people after their deaths—not only as static replicas but as evolving digital entities that may steer companies or influence world events.

Experts are exploring ways artificial intelligence might confer a kind of digital immortality, preserving the personalities of the departed in virtual form and then allowing them to evolve.

The Gist: They think they can start wider human trials soon which would last 2 years then have a product in 3 to 4 years.

In this video, Drs Irina and Mike Conboy talk how TPE, therapeutic plasma exchange is already available as an FDA approved procedure and the plans to extend the usage to include more age related diseases. We also discuss the company that they have formed IMU

Continue reading “Translating Blood Plasma Dilution To Humans | Drs. Irina & Mike Conboy Interrview Series Ep3” »

Did you know that life extension is impossible? I didn’t until the keen minds over at the Guardian informed me as such. Fortunately before I decided to give up my career in regenerative medicine I decided to look into exactly how the Guardian came to such a revelation. What I discovered was so earth shattering that it rocked my very understanding of the world, and made me question everything I thought I knew. That realisation was that, despite their consistent insistence to the contrary, the media lies, a lot.

Ok maybe this was not as shocking as I made it out to be, in fact it’s pretty widely known by now that the media is generally no stranger to the odd lie here and there. If you are not familiar with the story allow me to give you a recap. A recent study was conducted in order to find out if human lifespans have actually increased due to advanced in medicine. To do this, scientists used statistical models to remove non-age related causes of death from historical records (such as murder, death in child birth, plague etc) in order to determine what the uninterrupted human lifespan is, and if it has increased over time. What was found is that our medical science is yet to fundamentally extend human lifespan. This comes as no surprise to anyone in the field of longevity research as we know full well that none of our current medical treatments address causes of ageing. What this study does not conclude however is that life extension is impossible.

US$8.5 Billion In Funding — 150+ Projects

Dr. Maria Millan, MD, is the President and CEO of the California Institute for Regenerative Medicine (CIRM — https://www.cirm.ca.gov/), an organization that was created in 2004 when voters initially approved a state Proposition which allocated US$3 billion to fund this fascinating area of medicine, and which recently received an additional US$5.5 billion in renewed funding.

Continue reading “Dr. Maria Millan, MD — President and CEO — California Institute for Regenerative Medicine (CIRM)” »

Not just the results, but the vector used. I’ll post the paper below.

In this video we cover an experiment where gene therapies to overexpress TERT and Follistatin were used in a mouse model. The mice saw a 41 and 32% increase in median life span. The study also used a novel viral vector, cytomegalovirus for the delivery. Please note that this a preprint which is not peer-reviewed yet.

Continue reading “Gene Therapy Basics” »

Antiaging gene therapies to overexpress TERT and Follistatin were used in a mouse model. The mice saw a 41 and 32% increase in median life span. The study also used a novel viral vector, cytomegalovirus for the delivery.

Liz Parish of Bioviva has treated herself with all of these antiaging gene therapies.

Continue reading “Antiaging Gene Therapies Extend Lifespan of Mice” »

Sun, Sep 12 at 12 PM PDT.

This is an invitation to the Annual General Meeting of the Cryonics Institute & the Immortalist Society.

The Cryonics Institute, Annual General Meeting (AGM) will be held at 3:00pm to 6:30pm on Sunday, September 12th, 2021 at the Infinity Hall 16650 E. 14 Mile Rd, Fraser, MI 48026 (USA) for more information visit www.infinityhallsidebar.com or call 586−879−6157. Tours at the CI facility will be from 1:00pm to 2:30pm 24355 Sorrentino Court, Clinton Township, (Michigan) 48035 (USA).

Continue reading “CI Annual General Meeting 2021” »

Not sure how interesting this will be to people who know a lot on aging/longevity research.

A team of researchers at Brigham and Women’s Hospital and Harvard Medical School have found evidence of mouse and human germline cells resetting their biological age. In their paper published in the journal Science Advances, the group describes their study of the aging process in germline cells and what they found by doing so.

As animals grow older, all of the cells in their body replicate themselves repeatedly. As the process continues, errors in replicating and other external factors (such as exposure to pollutants) lead to gradual decay in cell quality, which is all part of the natural aging process. In this new effort, the researchers have found evidence showing that germline cells have a mechanism for resetting this process, allowing offspring to reset their aging clocks.

Continue reading “Mouse and human germline cells appear to reset their biological age” »