Lifeboat Foundation

Longer, Healthier, And More Productive Lives — Dr. Jean Accius Ph.D., Senior Vice President, AARP

Dr. Jean C. Accius, PhD, is Senior Vice President, AARP Global Thought Leadership (https://www.aarp.org/). Dr. Accius leads a team in positioning AARP (formerly known as the American Association of Retired Persons) as a global thought leader, identifying emerging trends around the world, cultivating and elevating new ideas, forging global strategic alliances that become the foundation for collaboration and sparking bold solutions to change systems and improve the lives of the global population as it ages.

Continue reading “Dr. Jean C. Accius, Ph.D. — Senior Vice President, AARP — Longer, Healthier, More Productive Lives” »

While is seems like the majority of the longevity space is currently overly captivated by the Aubrey de Grey/SENS debacle, the U.S. National Academy of Sciences, Healthy Longevity Global Innovator Summit is now beginning — Most interestingly, former R&D Head at PepsiCo, Dr. Mehmoud Khan, will be speaking in his new role as CEO of the Hevolution Foundation; a potential multi-billion $$$ initiative with a longevity angle — Everyone should keep their eye on this one…

The National Academy of Medicine (NAM) will hold its inaugural Healthy Longevity Global Innovator Summit in September 2,021 with support from Johnson and Johnson Innovation and The John A. Hartford Foundation. The event will be virtual and held over three days, September 13 14, and 22 and feature an immersive, interactive digital venue with unique opportunities to engage and connect.

The Innovator Summit will honor the 154 international Healthy Longevity Catalyst Awardees from 2020 and bring together industry leaders, academics, researchers, scientists, and entrepreneurs whose work contributes to the field of healthy longevity. Attendees will learn about the early-stage, award-winning innovations, hear from leaders in the field of healthy longevity, and take advantage of various opportunities to interact directly with other attendees, with a view to fostering interdisciplinary and cross-sector collaboration.

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As we age, our bones become thinner, we suffer fractures more often, and bone-diseases such as osteoporosis are more likely to occur. One responsible mechanism involves the impaired function of the bone-marrow stem cells, which are required for the maintenance of bone integrity. Researchers from the Max Planck Institute for Biology of Ageing and CECAD Cluster of Excellence for Ageing Research at the University of Cologne have now shown that the reduced stem cell function upon aging is due to changes in their epigenome. They were able to reverse these changes in isolated stem cells by adding acetate. This fountain of youth for the epigenome could become important for the treatment of diseases such as osteoporosis.

Aging Researchers have been looking at epigenetics as a cause of aging processes for some time. Epigenetics looks at changes in genetic information and chromosomes that do not alter the sequence of the genes themselves, but do affect their activity. One possibility is changes in proteins called histones, which package the DNA in our cells and thus control access to DNA. The Cologne research group of Peter Tessarz has now studied the epigenome of mesenchymal stem cells. These stem cells are found in bone marrow and can give rise to different types of cells such as cartilage, bone and fat cells.

With all that said, it’s natural for humans to crave and eat limited amounts of sugar. After going through all the research, here’s what I am doing for myself.

For example, foods high in fructose stimulate ghrelin while suppressing leptin—hormones responsible for hunger and satiety. Sugar can promote chronic hyperglycemia, which can both lead to weight gain and is another risk for diabetes. And sugary drinks, especially, are tied directly to obesity.

Sugar and aging: a bad combination (so what should we do?)

Continue reading “Sugar and Aging: What You Need to Know” »

X-Prize board member Sergey Young on his new book, and the potential for a longevity X-Prize.

“We have created science and technology to extend our life, but we haven’t created life we want to extend.”–Sergey Young, Seeking Delphi™ episode #55, explaining why he believes more people do not support radical life extension.

Continue reading “#55: The Longevity Dialogs Part 3, The Science and Technology of Growing Young with Sergey Young” »

One of the many areas graphene promises to have transformative effects is in fortifying construction materials like concrete and asphalt. A first-of-a-kind trial now underway seeks to apply the wonder material’s impressive attributes to one of the UK’s major thoroughfares, by deploying it in a road resurfacing project along a stretch of the A1 motorway.

Made up of a single sheet of carbon atoms arranged in a honeycomb pattern, graphene offers incredible strength and flexibility, and by incorporating it into materials like asphalt scientists hope to develop road surfaces that last far longer, and therefore cost less to maintain.

Back in 2017 we looked at an interesting take on this from a pair of Italian companies that developed an asphalt material doped with a graphene additive to make it less likely to soften in the heat and crack in the cold under high loads. This product, known as Gipave, also incorporates plastic pellets and was recently rolled out along stretches of UK roads as part of trials to see how it can extend the lifespan of the surface.

In humans, as well as all vertebrate animals, turning a fertilized egg into an embryo with a little beating heart requires that stem cells differentiate, specialize, and generate specific tissues, such as bones, blood vessels and a nervous system. This process is kickstarted and regulated by retinal. Animals can’t produce their own retinal, though, they must ingest it from plants, or from animals that eat plants.

Plant roots and animal embryos rely on the same chemical for successful development.

What do frog eggs have in common with anti-aging creams? Their success depends on a group of chemical compounds called retinoids, which are capable of generating and re-generating tissues.

Continue reading “Growth-Promoting, Anti-Aging Chemical Compound at the Root of Plant Growth and Animal Embryos” »

Check out our second promo for #transvision #future Summit 2021 (#madrid Oct. 8 — 12), featuring the optional dinner/cocktails we are scheduling, and 2 full-day #tours of several #unescoworldheritage sites and historical places near Madrid: Segovia, Ávila, Monsaterio de El Escorial & Valley of the Fallen on Oct. 11 and Alcalá de Henares, Aranjuez & Toledo on Oct. 12. It’s going to be espectacular! You don’t wanna miss those, so get your tickets now! 😊 Get your tickets here -> www.TransVisionMadrid.com.

The event itself will be a lot of fun, so make sure to register to come to Madrid in person, or to watch it via streaming (at a reduced price). There will be talks about #longevity #artificialintelligence #cryonics and much much more.

Continue reading “#TransVision Future Summit 2021 • Welcome to Madrid 8 — 12 October • Dinners & UNESCO site tours” »

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Levine’s Biological age calculator is embedded as an Excel file in this link from my website:
https://michaellustgarten.com/2019/09/09/quantifying-biological-age/

Continue reading “Quantifying Biological Age: Blood Test #4 in 2021” »