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Archive for the ‘life extension’ category: Page 225

Oct 3, 2021

Staying Young: Scientists Discover New Enzymatic Complex That Can Stop Cells From Aging

Posted by in categories: biotech/medical, life extension

Scientists in Montreal discover a new enzymatic complex that can stop cells from aging, opening the way to possible new cancer therapies.

Researchers at Université de Montréal and McGill University have discovered a new multi-enzyme complex that reprograms metabolism and overcomes “cellular senescence,” when aging cells stop dividing.

In their study published on September 16 2021, in Molecular Cell, the researchers show that an enzyme complex named HTC (hydride transfer complex) can inhibit cells from aging.

Oct 1, 2021

New foundation will distribute $1bn for aging research

Posted by in categories: biotech/medical, life extension

“The Foundation has created a unique and transparent mechanism for boosting early longevity research worldwide and ensuring mass public participation in decision making,” said Alex Zhavoronkov, Visionary Board member and an expert in AI-powered drug discovery. “This approach finally allows us to speak about getting closer to the idea of mass adoption of longevity ideas and treatments.”

“Age is the greatest risk factor for nearly every major cause of death and disability in developed nations. Therapeutically targeting biological aging is key to fulfilling the promise of 21st century medicine, and the Foundation is poised to play a central role in making this a reality,” said Matt Kaeberlein, CEO of the American Aging Association and Professor at the University of Washington, where he leads several major initiatives.

“In five years, healthy longevity will not only exist as a lab-proven concept, but will become part of everyone’s life,” said Andrea Maier, Visionary Board member and co-director of the Centre for Healthy Longevity at the National University of Singapore.

Oct 1, 2021

Higher rates of mutation alone are not to blame for age-related disease

Posted by in categories: biotech/medical, genetics, life extension

New research exploring theories of aging has found that small mutations accumulating in DNA are unlikely to be fully responsible for this process.

The research, a collaboration between the Wellcome Sanger Institute, University of Birmingham, University of Edinburgh and others, found that and tissues can accumulate many more than are normally present, without the body showing the features associated with aging.

The new study, published today (30 September) in Nature Genetics, compared DNA taken from individuals with inherited mutations in genes involved in DNA replication with DNA from individuals who have normal versions of these genes. The researchers aimed to understand the impact of defective DNA replication on and features associated with aging. The results suggest that build-up of mutations in is unlikely to be the only factor in the development of age-related disease, adding to the ongoing debate about the causes of aging.

Oct 1, 2021

Dr. Evelyne Bischof, MD — Advancing The Frontiers Of Preventative And Precision Longevity Medicine

Posted by in categories: biotech/medical, genetics, life extension, robotics/AI

(https://www.linkedin.com/in/evelyne-yehudit-bischof/) is an expert in internal medicine and oncology, with a focus on preventative and precision medicine, bio-gerontology, and geronto-oncology.

Dr. Bischof is deeply passionate about next-generation medical technology, and the applications of artificial intelligence for biomedical research and practice.

Continue reading “Dr. Evelyne Bischof, MD — Advancing The Frontiers Of Preventative And Precision Longevity Medicine” »

Sep 30, 2021

No Shame In Wanting To Look Younger — It Is Natural And You Might As Well Live Longer

Posted by in categories: biological, evolution, life extension

Like many other living organisms, humans are born, survive, compete for resources, reach maturity, reproduce, take care of their young, sometimes the young of their young, continuously decline, and die. Evolution needs us for just two purposes – adapt and reproduce. But, unlike other species, humans are very conscious of their fate. Humans are very much aware that after reaching peak performance they will eventually grow old and die. We are very conscious of our fate after reaching peak performance – loss of function, frailty, and eventual loss of everything we worked so hard to earn.

We observe our parents, and other elderly around them, attend funerals, and understand that eventually we will get into this state. We are also very contempt with that fate as evolution made sure that. The more ambitious of us are trying to advance science, the rest seek refuge in religion, some in philosophy, some in accumulation of wealth, and some see the continuation of ourselves in our children. But despite the many technological advances transpiring in the laboratories all over the world, there is nothing we can do at this point to escape aging. There are diets, exercises, sleep, and supplements, but these provide very marginal benefits. We do not see 120+ old yoga and diet practitioners or marathon runners around. But these simple habits do help look younger longer. And many people that have very harmful habits like smoking but still diet and exercise to look younger.

Sep 30, 2021

$1B longevity fund launches to pursue 120+ lifespan

Posted by in categories: biotech/medical, life extension, robotics/AI

$100 million a year. All you gotta do is apply for funding.


A consortium of biotech founders, clinicians, and leading longevity research institutions announced today the launch of the Longevity Science Foundation. The new Swiss foundation has committed to distributing more than $1 billion over the next ten years to research, institutions and projects advancing healthy human longevity and extending the healthy human lifespan to more than 120 years.

Longevity. Technology: The Foundation is advised by a aptly-named “Visionary Board” of leading longevity researchers, led by Evelyne Bischof and joined by Andrea B Maier, Eric Verdin, Matt Kaeberlein and Alex Zhavoronkov, all key opinion leaders who be top picks for a longevity dream team.

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Sep 30, 2021

New Insights Into How Metabolism Changes Over the Human Lifespan

Posted by in categories: biotech/medical, life extension

Metabolism and total energy expenditure change throughout our lives, and now a new study documents a series of distinct, related changes in unprecedented detail. The data – drawn from a large cohort of humans spanning from birth to old age – shed new light on human development and aging and could help shape targeted nutrition and health strategies across the human lifespan.

The complex machine that is the human body requires a substantial amount of energy to fuel day-to-day physical activity and sustain life. However, while energy use is central to understanding many aspects of human health and physiology, including daily nutritional requirements and metabolic investment in myriad activities, very little is known about total energy expenditure in humans or how it varies over the human lifespan.

Most large-scale surveys of human energy expenditure have focused on basal expenditure, which only accounts for roughly half of total expenditure. And, while doubly labeled water (DLW) studies can provide a measure of total energy expenditure in free-living individuals, they, too, are often limited in sample size and diversity.

Sep 29, 2021

Bill Andrews on age reversal and the Betty White Test (videoclip con S/T en Español)

Posted by in categories: biological, life extension

Bill Andrews gives us the simplest definition of aging as well as what he thinks to be accomplished to really admit aging has been cured.

This is an excerpt of a presentation he made last year at the NHIMA. See the description of the video for details.

Continue reading “Bill Andrews on age reversal and the Betty White Test (videoclip con S/T en Español)” »

Sep 29, 2021

Has the fountain of youth been in our blood all along?

Posted by in categories: biotech/medical, life extension

The search for a fountain of youth has obsessed humankind for millennia, but a new wave of research is showing that the secret may have been running through our veins all along.

Sep 27, 2021

Dr Jennifer Garrison, PhD — Global Consortium for Reproductive Longevity & Equality — Buck Institute

Posted by in categories: biotech/medical, chemistry, life extension, neuroscience

Dr. Jennifer Garrison, PhD (http://garrisonlab.com/) is Assistant Professor, Buck Institute for Research on Aging, Founder & Faculty Director, Global Consortium for Reproductive Longevity & Equality (https://www.buckinstitute.org/gcrle/), Assistant Professor in Residence, Cellular and Molecular Pharmacology, UCSF and Adjunct Assistant Professor of Gerontology, USC Leonard Davis School of Gerontology.

Dr. Garrison’s lab is interested in understanding how neuropeptides (a large class of signaling molecules which are secreted from neurons and transmit messages within the brain and across the nervous system) regulate changes in normal and aging animals as well in understanding how they control behavior at both the cell biological and neural circuit level.

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