Lifeboat Foundation

Eight cutting-edge heart failure projects are set to receive millions of pounds’ worth of funding from the British Heart Foundation (BHF) this year, with the money raised, fittingly enough, by the London Marathon.

Longevity. Technology: Heart disease is the world’s greatest killer, with cardiovascular diseases (CVDs) taking an estimated 17.9 million lives each year [1]. With organs for transplant in short supply, the focus is turning to regenerative medicine – getting the heart to repair itself – and the BHF is planning to fund eight projects all aimed at finding ways to cure heart failure. Given that a picture paints a thousand words, BHF has made the smart move of showcasing this regenerative research through a stunning set of images that shows the Foundation’s desire to not just ameliorate the symptoms of heart disease, or to extend patients’ lives, but to cure heart disease by regenerating, regrowing or replacing damaged cells and tissues.

“Heart failure is a debilitating condition that dramatically affects the lives of almost 1 million people in the UK,” commented Professor Metin Avkiran, BHF Associate Medical Director. “BHF-funded research has spear-headed treatments to give people with heart failure longer, healthier lives, but there is no cure. Regenerative medicine offers that hope.

It’s not a new fact that with age comes several problems, especially if you don’t take care of yourself. This applies to eyesight as well; as you grow old, the chances of you facing vision-related problems are high. And unfortunately, some people do suffer from one or more vision-related issues.

But there is a way in which this problem can be overcome. Several supplements are available to help you improve your vision, and they can help you address vision-related issues in a much more efficient manner. There are several vision-related problems, and likewise, there are supplements that tackle multiple vision problems and provide you with relief.

But the harsh truth is that not every supplement is made the same, meaning not all supplements are safe to use. This is the main reason why people are a little skeptical about purchasing any kind of dietary supplement.

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Papers referenced in the video:
Melatonin, human aging, and age-related diseases.
https://pubmed.ncbi.nlm.nih.gov/15582288/

Continue reading “Middle-of-the-Night Melatonin Supplementation: Better Sleep, Improved HRV and RHR?” »

The basics for tracking include blood biomarkers that have been studied for 50 – 100+ years, depending on the biomarker. Most of these biomarkers are commonly measured at a yearly physical, and are relatively cheap (35 $USD for the standard chemistry panel and complete blood count).

A nanomaterials-engineered penetrating sealer developed by Washington State University researchers is able to better protect concrete from moisture and salt—the two most damaging factors in crumbling concrete infrastructure in northern states.

The novel sealer showed a 75% improvement in repelling water and a 44% improvement in reducing salt damage in laboratory studies compared to a commercial sealer. The work could provide an additional way to address the challenge of aging bridges and pavements in the U.S.

“We focused on one of the main culprits that compromises the integrity and durability of concrete, which is moisture,” said Xianming Shi, professor in the Department of Civil and Environmental Engineering who led the work. “If you can keep concrete dry, the vast majority of durability problems would go away.”

Sometimes those working in the field of rejuvenation biotechnology face the accusation that what they are doing is just a fear of death, like not being scared of age-related diseases is somehow brave.

War used to be fashionable but now it isn’t

Continue reading “Some People think Life Extension is ‘Just a Fear of Death’” »

Our furry friends are about to fetch new answers to the tough problem of longevity.

The Dog Aging Project (DAP), launched in 2018, is recruiting tens of thousands of loyal canine companions for a comprehensive study. The open-sourced collaborative project, expected to last ten years, has ambitious goals: tackle the thorny problem of what contributes to aging, and test ways to prolong healthy longevity.

Aside from its massive scale—it’s the largest data-gathering program of its kind—the project stands out in that it eschews the usual method of using lab animals, grown in carefully-controlled environments and often inbred. Instead, DAP is recruiting dogs from across the country, with a smorgasbord of breeds, ages, and environments.

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Papers referenced in the video:
Main study:
Clinical course of the longest-lived man in the world: A case report.
https://pubmed.ncbi.nlm.nih.gov/34973348/

Continue reading “(Part II) Supercentenarian (112 — 116y) Blood Test Analysis” »