Lifeboat Foundation

Transforming base materials into gold was one of the elusive goals of the alchemists of yore. Now Professor Raffaele Mezzenga from the Department of Health Sciences and Technology at ETH Zurich has accomplished something in that vein. He has not of course transformed another chemical element into gold, as the alchemists sought to do. But he has managed to recover gold from electronic waste using a byproduct of the cheesemaking process.

Electronic waste contains a variety of valuable metals, including copper, cobalt, and even significant amounts of gold. Recovering this gold from disused smartphones and computers is an attractive proposition in view of the rising demand for the precious metal.

However, the recovery methods devised to date are energy-intensive and often require the use of highly toxic chemicals. Now, a group led by ETH Professor Mezzenga has come up with a very efficient, cost-effective, and above all far more sustainable method: with a sponge made from a protein matrix, the researchers have successfully extracted gold from electronic waste.

Roughly 4 billion years ago, Earth was developing conditions suitable for life. Origin-of-life scientists often wonder if the type of chemistry found on the early Earth was similar to what life requires today. They know that spherical collections of fats, called protocells, were the precursor to cells during this emergence of life. But how did simple protocells first arise and diversify to eventually lead to life on Earth?

Now, Scripps Research scientists have discovered one plausible pathway for how protocells may have first formed and chemically progressed to allow for a diversity of functions.

The findings, published online on February 29, 2024, in the journal Chem, suggest that a chemical process called phosphorylation (where phosphate groups are added to the molecule) may have occurred earlier than previously expected. This would lead to more structurally complex, double chained protocells capable of harboring chemical reactions and dividing with a diverse range of functionalities. By revealing how protocells formed, scientists can better understand how early evolution could have taken place.

They designed persistent epigenetic silencing.

Changes to chemical tags on DNA in mice dial down the activity of a gene without cuts to the genome.

Webb telescope observes potentially young Methane deposits on surfaces of Eris, Makemake. A team co-led by Southwest Research Institute found evidence for hydrothermal or metamorphic activity within the icy dwarf planets Eris and Makemake, located in the Kuiper Belt. Methane detected on their surfaces has the tell-tale signs of warm or even hot geochemistry in their rocky cores, which is markedly different than the signature of methane from a comet.

“We see some interesting signs of hot times in cool places,” said SwRI’s Dr. Christopher Glein, an expert in planetary geochemistry and lead author of a paper about this discovery.

The Kuiper Belt is a vast donut-shaped region of icy bodies beyond the orbit of Neptune at the edge of the solar system.

A pilot study but possibly concerning. A banned pesticide found in Cheerios and Quaker oats. They suggest sticking to organic. The pesticide got in there by importing ingredients.

This week, the Environmental Working Group, revealed findings from a study that shows that chlormequat chloride, a chemical banned in the U.S. was found in some of our favorite cereals. Here’s what the experts say.

Wonderful work truly breakthrough for different types of compounds for chemistry. Year 2021.

V-SYNTHES, a scalable and computationally cost-effective synthon-based approach to compound screening, identified compounds with a high affinity for CB2 and CB1 in a hierarchical structure-based screen of more than 11 billion compounds.

Molecules that are induced by light to rotate bulky groups around central bonds could be developed into photo-activated bioactive systems, molecular switches, and more.

Researchers at Hokkaido University, led by Assistant Professor Akira Katsuyama and Professor Satoshi Ichikawa at the Faculty of Pharmaceutical Sciences, have extended the toolkit of synthetic chemistry by making a new category of molecules that can be induced to undergo an internal rotation on interaction with light. Similar processes are believed to be important in some natural biological systems.

Synthetic versions might be exploited to perform photochemical switching functions in molecular computing and sensing technologies or in bioactive molecules, including drugs. Their report is pending in Nature Chemistry.

Measuring the precise quantity of rainfall in a particular area is straightforward when there is equipment specifically designed to accurately capture and relay precipitation data. However, quantifying and identifying the types of precipitation across all locations on Earth presents significant logistical challenges.

Importantly, this information could provide a wealth of data for characterizing and predicting Earth’s water, energy, and biogeochemical cycles. Researchers from China recently deployed a satellite, FengYun 3G (FY-3G), that is successfully collecting Earth precipitation data from space.

We conducted a multicenter, nested case–control study of Alzheimer’s disease biomarkers in cognitively normal participants who were enrolled in the China Cognition and Aging Study from January 2000 through December 2020. A subgroup of these participants underwent testing of cerebrospinal fluid (CSF), cognitive assessments, and brain imaging at 2-year–to–3-year intervals. A total of 648 participants in whom Alzheimer’s disease developed were matched with 648 participants who had normal cognition, and the temporal trajectories of CSF biochemical marker concentrations, cognitive testing, and imaging were analyzed in the two groups.

The median follow-up was 19.9 years (interquartile range, 19.5 to 20.2). CSF and imaging biomarkers in the Alzheimer’s disease group diverged from those in the cognitively normal group at the following estimated number of years before diagnosis: amyloid-beta (Aβ)₄₂, 18 years; the ratio of Aβ₄₂ to Aβ₄₀, 14 years; phosphorylated tau 181, 11 years; total tau, 10 years; neurofilament light chain, 9 years; hippocampal volume, 8 years; and cognitive decline, 6 years. As cognitive impairment progressed, the changes in CSF biomarker levels in the Alzheimer’s disease group initially accelerated and then slowed.

In this study involving Chinese participants during the 20 years preceding clinical diagnosis of sporadic Alzheimer’s disease, we observed the time courses of CSF biomarkers, the times before diagnosis at which they diverged from the biomarkers from a matched group of participants who remained cognitively normal, and the temporal order in which the biomarkers became abnormal. (Funded by the Key Project of the National Natural Science Foundation of China and others; ClinicalTrials.gov number, NCT03653156. opens in new tab.)