Lifeboat Foundation

The futuristic gizmo will launch this month.

The loss of complete segments of the esophagus often results from treatments for esophageal cancer or congenital abnormalities, and current methods to re-establish continuity are inadequate. Now, working with a rat model, researchers have developed a promising reconstruction method based on the use of 3D-printed esophageal grafts. Their work is published in Tissue Engineering, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

Eun-Jae Chung, MD, PhD, Seoul National University Hospital, Korea, Jung-Woog Shin, PhD, Inje University, Korea, and colleagues present their research in an article titled “Tissue-Engineered Esophagus via Bioreactor Cultivation for Circumferential Esophageal Reconstruction”. The authors created a two-layered tubular scaffold with an electrospun nanofiber inner layer and 3D-printed strands in the outer layer. After seeding human mesenchymal stem cells on the inner layer, constructs were cultured in a bioreactor, and a new surgical technique was used for implantation, including the placement of a thyroid gland flap over the scaffold. Efficacy was compared with omentum-cultured scaffolding technology, and successful implantation and esophageal reconstruction were achieved based on several metrics.

Dr. Chung and colleagues from Korea present an exciting approach for esophageal repair using a combined 3D printing and bioreactor cultivation strategy. Critically, their work shows integration of the engineered esophageal tissue with host tissue, indicating a clinically viable strategy for circumferential esophageal reconstruction.”

Ongoing and future space missions, rising investment in new mining technologies, and the use of materials obtained from asteroids in 3D printing will drive the growth of the asteroid mining market, according to Allied Market Research.

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A 3D-printed prosthetic hand controlled using a new AI-based approach could significantly lower the cost of bionic limbs for amputees.

Real need: There are approximately 540,000 upper-limb amputees in the United States, but sophisticated “myoelectric” prosthetics, controlled by muscle contractions, are still very expensive. Such devices cost between $25,000 and $75,000 (not including maintenance and repair), and they can be difficult to use because it is hard for software to distinguish between different muscle flexes.

Handy invention: Researchers in Japan came up with a cheaper, smarter myoelectric device. Their five-fingered, 3D-printed hand is controlled using a neural network trained to recognize combined signals—or, as they call them, “muscle synergies.” Details of the bionic hand are published today in the journal Science Robotics.

New 3D-printed materials are going to space thanks to a recently funded partnership between Israel’s NanoDimension and Florida’s Harris Corp.

The companies plan to create new materials to reduce the manufacturing of small satellites, an exceedingly popular market right now for applications ranging from weather observations to remote surveillance.

They aim to fly their materials on an external platform of the International Space Station for a year. The goal is to better understand how 3D-printed components (such as circuits and materials) withstand the space environment, which includes extreme temperature swings and high radiation. The launch date of the project was not disclosed.

An exciting breakthrough from Columbia University researchers demonstrates a new way to grow human hair follicles using 3D printed molds. This is the first time human hair follicle cells have been grown completely in lab conditions, opening up a potentially unlimited source of hair follicles for future hair restoration surgical procedures.

On a sofa in the corner of the room, a cat is purring. It seems obvious that the cat is an example of life, whereas the sofa itself is not. But should we trust our intuition? Consider this: Isaac Newton assumed a universal time flowing without external influence, and relative time measured by clocks – just as our perception tells us. Two centuries later, Albert Einstein dropped the concept of universal time, and instead introduced a concept of time measured only locally by clocks. Who before Einstein would have thought that time on the Sun, the Moon, and even on each of our watches runs at slightly different rates – that time is not a universal absolute? And yet today our cellphones must take this into account for a GPS to function.

Life ≠ alive.

A cat is alive, a sofa is not: that much we know. But a sofa is also part of life. Information theory tells us why.

Continue reading “What can Schrödinger’s cat say about 3D printers on Mars? Essays” »

Though it may be hard to believe that there is already an “established” method of doing something such as 3D-printing biological tissue, there does indeed seem to be one. It utilizes microscale scaffolds – which a newly-developed technique does away with the need for.