Researchers at University of California San Diego School of Medicine and their colleagues have developed the first comprehensive map of the dramatic changes that take place in the blood system over the course of the human lifetime.
The study was published on December 5 in Nature Methods.
The team quantified the gene expression of more than 58,000 individual hematopoietic (blood) stem cells at seven stages, from early fetal development to old age. They documented consistent changes in the types of blood cells that are produced in response to the functional demands of each life stage.
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