Lifeboat Foundation

MOUNTAIN VIEW, Calif. — July 11, 2016 — SENS Research Foundation today announced its Project|21 campaign to secure $50 million in private support from individual donors, foundations, and corporations. The goal of Project|21 is for SRF to partner with a new generation of visionary philanthropists, build the Rejuvenation Biotechnology industry, and bridge the most challenging gulf between research and treatment by enabling human clinical trials by 2021.

Aubrey de Grey, founder and chief science officer of SENS Research Foundation said, “Ending aging will require large-scale investment to flow into a globally-recognized industry for rejuvenation biotechnology. Since we began in 2009, SENS Research Foundation has been putting all the pieces in place — core research groups, key players, shared knowledge, underlying tools — for the creation of this industry. The key programs funded by Project|21 can create an environment where the first damage repair interventions addressing specific age-related diseases will be brought to human clinical trials within five years.”

The programs funded under Project|21 focus on three major barriers to the development of truly effective rejuvenation therapies. First, funding to convert promising basic research programs into solid investment candidates remains far too scarce. Second, there are too few opportunities for dynamic collaborations with mainstream regenerative medicine. Finally, there is little understanding of the regulatory pathways and clinical infrastructure these technologies will require. Project|21 addresses these three areas by creating a $15 million bridge fund to support promising early stage technologies; a center of excellence to deliver better opportunities for collaborative development of early stage programs; and a Rejuvenation Biotechnology Alliance Program to address challenges in regulation, manufacturing, and investment.

Continue reading “Project|21 SENS Research Foundation | Building the Bridge to Human Clinical Trials for Rejuvenation Biotechnologies” »

A research team at the University of Washington has harnessed complex computational methods to design customized proteins that can self-assemble into 120-subunit “icosahedral” structures inside living cells—the biggest, self-booting, intracellular protein nanocages ever made. The breakthrough offers a potential solution to a pressing scientific challenge: how to safely and efficiently deliver to cells new and emerging biomedical treatments such as DNA vaccines and therapeutic interfering particles.

The work, funded by DARPA in a lead-up to the new INTERfering and Co-Evolving Prevention and Therapy (INTERCEPT) program, “opens the door to a new generation of genetically programmable protein-based molecular machines,” the researchers report in this week’s issue of the journal Science. The research paper is available here: http://ow.ly/LW8F302tOp3

Anyone familiar with the role-playing games Dungeons and Dragons and Munchkin need only picture the 20-sided die to understand what an organic, icosahedral cargo container looks like—symmetrical, triangle-shaped panels folded evenly on each side. Unlike a die that can be held in your hand, however, these creations are the size of small viruses and are designed to interact with cells in the same way viruses might—that is, by delivering their caged contents into a cell, albeit in this case with positive, customizable outcomes. Also, whereas dice are produced in molds on a factory assembly line, these nanocages build themselves inside cells, following with atomic precision instructions written in genetic code.

No offense Tesla, Google, GM, etc.

China has banned highway testing of autonomous vehicles while the country’s auto-industry regulator works with local police to determine specific national rules about autonomous car testing.

Beneath the vast area in the South China Sea is potentially oil-rich grounds enough to give any country’s economy a significant boost, reports show.

When buying an iPhone in China can get you fired. My guess his motto is “Lets Make China Great Again”.

The patriotic boss in Hangzhou has also offered cash rewards of up to 2,500 Yuan for employees to switch to made-in-China phones.

Russia has agreed to build a nuclear-powered aircraft carrier jointly with India.

According to sources close to the Indian Navy, Kremlin recently sent a letter to the Indian Defence Ministry in which the offer was made. A senior Navy officer told the press: “A Russian military delegation offered India the Project 23000E ‘Storm’ (E stands for export-oriented, Eksportny) heavy aircraft carrier several weeks ago.” The officer, who wished to remain anonymous, said that the Narendra Modi government was considering the offer and would make a final decision soon.

Speaking at a press conference in the Indian capital a couple of days ago, the officer said: “The surface combatant is known to have a full displacement of about 100,000 tonnes and a price of about USD 5.7 billion. The proposed carrier has been jointly developed by the Krylov State Research Centre (KGNC) and the Nevskoye Design Bureau (NPKB), a subsidiary of the United Shipbuilding Corporation. The building of the Project 23300 ‘Storm’ aircraft carrier is supposed to take about 10–11 years.”

Continue reading “Russia Ready To Build Nuke-Powered Aircraft Carrier For India” »

Hmmm.

The technical details of air-to-air missiles are extremely complicated, but the concept is simple — destroy your target before the target destroys you.

One way to improve the odds is to add an air-breathing ramjet engine to give the weapon a boost. That’s the design philosophy behind the Meteor, a 419-pound rail-launched MiG killer which entered service for the first time with the Swedish air force on July 11.

Continue reading “This unstoppable missile has Russia in its sights” »

https://youtube.com/watch?v=v4qqIjRkuxk

Amazing art.

Repetitive strokes of spray paint make up these eye-popping murals that transform boring urban landscapes.

SoftBank’s ARM acquisition was 40 years in the making.