Lifeboat Foundation

The official start of Atlantic Hurricane Season is less than six weeks away, and forecasters will be getting an essential upgrade just in time for the season to begin.

New technology from the University of Wisconsin will help with preparation of more detailed forecasts and provide more reliable information to meteorologists and emergency planners, which should ultimately result in better, safer outcomes for public safety.

The Advanced Dvorak Technique (ADT) is a satellite-based method for determining tropical cyclone intensity. Planned upgrades include the use of full-resolution images from weather satellites, better identification of the location of each storm’s eye and the ability to better analyze hurricanes occurring outside tropical regions.

NASA has picked SpaceX, Amazon and four other American companies to develop the next generation of near-Earth space communication services meant to support its future missions. The agency started looking for partners under the Communication Services Project (CSP) in mid-2021, explaining that the use of commercially provided SATCOM will reduce costs and allow it to focus its efforts on deep space exploration and science missions.

“Adopting commercial SATCOM capabilities will empower missions to leverage private sector investment that far exceeds what government can do,” NASA wrote in the official project page. By using technology developed by commercial companies, the agency will have continued access to any innovation they incorporate into the system. At the moment, NASA relies on its Tracking and Data Relay Satellite (TDRS) system for near-Earth space communications. Many of its satellites were launched in the 80’s and 90’s, though, and it’s set to be decommissioned in the coming years.

The funded agreements under NASA’s Communication Services Project has a combined value of $278.5 million, with SpaceX getting the highest cut. NASA expects the companies to match and exceed its contribution during the five-year development period. SpaceX, which proposed a “commercial optical low-Earth orbiting relay network for high-rate SATCOM services,” has been awarded $69.95 million. Amazon’s Project Kuiper is getting the second-highest cut and has been awarded $67 million, while Viasat Incorporated has been awarded $53.3 million. The other three awardees are Telesat US Services ($30.65 million), SES Government Solutions ($28.96 million) and Inmarsat Government Inc. ($28.6 million).

Circa 2021

As described above, molecular therapeutics enabling expression of a truncated dystrophin have been far developed. However, an unprecedented opportunity to correct the disease-causing mutation has arisen with the advent of Crispr-Cas9 technology (Fig. 1).

Since the generation of a Cas9-transgenic mouse [28], which allowed for pinpoint gene alterations specifically in organs targeted by AAVs encoding for the corresponding guide RNAs (gRNAs), it became clear that the inevitable course of inherited diseases might be altered by Cas9-mediated correction. Although certain limitations were unmasked early on, such as the preference of non-homologous end-joining (NHEJ) over homology-directed repair (HDR) upon enzymatic cleavage of the double stranded DNA by Cas9, or the packaging capacity of AAVs, muscular dystrophies seemed an ideal target for genome editing. DMD mutations inducing Duchenne muscular dystrophy (DMD) seemed particularly well suited, since internal truncations of the protein may lead to a shortened but stable protein with partial functional restitution and a milder disease progression, as seen in the allelic Becker muscular dystrophy (BMD).

Continue reading “Genome editing for Duchenne muscular dystrophy: a glimpse of the future?” »

A recent satellite hacking shows that end-of-life satellites may be vulnerable.

Israel punches above its weight in space science and exploration, as it does in most other arenas.

For example, the country developed its own line of orbital rockets, the Shavit (“Comet”) series, which has lofted a number of satellites over the years. And in April 2019, Israel’s Beresheet (“In the Beginning”) mission attempted to put a robotic lander down on the moon, something achieved only by the United States, the USSR/Russia and China — and nearly succeeded.

WASHINGTON – The U.S. Space Force in 2025 plans to launch to geostationary orbit three small satellites that will attempt to dock with a propellant tanker so they can be refueled in space.

The idea is to “test out pieces of the refueling infrastructure,” Col. Joseph Roth, director of innovation and prototyping at U.S. Space Systems Command, told SpaceNews last week at the Space Symposium in Colorado Springs.

The $50 million experiment, called Tetra-5, is run by the Space Force’s Space Enterprise Consortium. Bids for the project closed earlier this month.

WASHINGTON – As Maxar Technologies’ satellites continue to collect images of Russia’s invasion of Ukraine, the company is working with customers so it can allocate more capacity to meet U.S. government needs, said Maxar’s CEO Daniel Jablonsky.

With four satellites in orbit, “a lot of times we don’t have a lot of spare capacity,” Jablonsky said in an interview last week at the Space Symposium in Colorado Springs.

“But we made accommodations with some of our other customers to be able to surge capacity for the U.S. and allies,” he said. The company also gets about 200 requests a day for imagery from news media organizations.

The first 3D model of Earth’s magnetosphere could help us better understand how satellites cope with space weather.