Lifeboat Foundation

Whether we’re staring at our phones, the page of a book, or the person across the table, the objects of our focus never stand in isolation; there are always other objects or people in our field of vision. How that visual “clutter” affects visual processing in the brain, however, is not well understood.

In a new study published Oct. 22 in the journal Neuron, Yale researchers show that this clutter alters how information flows in the brain, as does the precise location of that clutter within the wider field of vision. The findings help clarify the neural basis of perception and offer a deeper understanding of the visual cortex in the brain.

Octopus arms may literally have a mind of their own. Each limb contains its own version of a spinal cord, called an axial nerve cord, and these cords collectively harbor most of the animal’s neurons.

The datasets provide “a very nice reference” for future functional studies.

stores and retrieves important information, such as domain-specific knowledge and memories. One dimension of human memory is the ability to link various aspects of experience to specific life events.

Past studies have suggested that this memory-related process is supported by phase precession, which is a shift in the timing at which specific neurons are fired. Up until now, however, this hypothesis had not been confirmed experimentally.

Researchers at the University of California, Davis, Harvard Medical School, Toronto Western Hospital and Cedars-Sinai Medical Center recently carried out a study aimed at probing the relationship between phase precession and memory.

The gut-brain axis has long been a subject of interest in lifespan research, and GLP-1 agonists, already used in the treatment of obesity and diabetes, are showing promise in the field of healthspan therapeutics.

New research on gut-to-brain signaling uncovers potential links between gut hormones like GLP-1 and longevity.

Intestinal stem cells play an important role in maintaining intestinal homeostasis and repairing damaged epithelial tissue. These cells function in a regenerative manner to generate new tissue throughout the growth phase and repair damaged tissue during the aging process.¹⁰¹ The interactions between the gut microbiome and intestinal stem cells are crucial because, if this interaction is comprehended, it may be possible to address various disorders that require stem cell therapy, heal wounds, and improve the durability of organ transplants.¹⁰¹ A recent study showed a connection between hematopoietic stem cells and the microbiome through altering metabolic stress.⁶⁶ Therefore, the microbiota is crucial for maintaining microbial homeostasis, regulating metabolism, and the innate and adaptive immune systems.¹⁰¹ Furthermore, the study reveals that compositional alterations in the gut microbiome driven by dysbiosis are related to stem cell aging, metabolic dysregulations, stem cells’ epigenetic instability, and abnormal immune system activation.⁶⁶

In the field of anti-aging, stem cells are regarded to have great potential. In numerous organs, it has been demonstrated that as we age, stem cells lose their capacity for self-renewal and differentiation and run out of resources.⁸⁹ The emergence of anti-aging medications should address the dysregulation caused by aging that affects stem cells’ capacity for differentiation and self-renewal by re-regulating intrinsic and extrinsic variables. The host microbiome, hormones, local immune system, systemic inflammation, and niche structure are just a few examples of microenvironmental and systemic factors that influence stem cell aging.⁶⁶

Endogenous ethanol is a class of microbiological metabolites. Proteobacteria, including E. coli and other Enterobacteriaceae, produce ethanol with bacterial origins. High endogenous ethanol levels in the human hippocampus inhibit proliferating stem cells and reduce progenitor and stem cells.¹⁰² Additionally, when more ethanol accumulates in the gut, it enhances the permeability of the gut by disrupting epithelial tight junctions, particularly zonula occludens. This enables the movement of pathogenic microbes, their endotoxins, and ethanol across the epithelial layer, causing more immediate and adverse effects on tissues. As a result, the stem cell reserve depletes, hastening the aging process and compensating for damaged tissues.¹⁰³

Fascinating as this may sound, not all dreams serve as gateways to parallel timelines. Whether dreams return is key here. “Recurring dreams, especially those with vivid and consistent scenarios, might suggest deeper connections to other realities,” Leong claims. On the other hand, dreams tied to personal experiences often feel disjointed, with distorted time. The most surreal and incomprehensible dreams are likely the subconscious processing your life here on Earth, he says. But, if it feels like you’re visiting the dream rather than imagining it—like a play with a beginning, middle, and end—you probably are visiting this other world, under Leong’s hypothesis.

Leong also hints that strong emotions in persistent dreams could offer cosmic clues—signals of how another version of you is experiencing life in a parallel world. “Say you have a repetitive dream of being stuck in high school,” he suggests. “While it may reflect unresolved psychological themes, such as feelings of stagnation or anxiety about personal growth, it could also indicate that in another reality, you are still in high school, dealing with the same challenges your waking self has moved beyond.” This emotional resonance—like the frustration of being stuck—could ripple across dimensions, creating a feedback loop between your conscious mind here and one of your alter egos elsewhere.

YET, AS CAPTIVATING AS THIS HYPOTHESIS MIGHT BE, it runs into a significant problem: there’s no empirical evidence to back it up. Quantum phenomena, such as entanglement and nonlocality, challenge our traditional views on time and space. Yet, no scientific studies conclusively support the idea that dreams are portals to other worlds. Mainstream neuroscience and cognitive science, on the other hand, find this hypothesis heretical—if not downright unscientific.

The incidence of breast cancer in women has increased significantly over the past few decades, but advancements in targeted therapies have led to a decrease in death…

Breast cancer cells send microRNA-filled vesicles to the brain, creating a nutrient-rich environment that facilitates metastasis.

3,024 likes, — getrealgetstrong on August 2, 2024: ‘Superhuman Capabilities lwith Neuralink’

For years, Dr. Schally and his rival in science, Roger Guillemin, scrambled to be first to confirm neurohormones. The Nobel Committee called it a tie.