Lifeboat Foundation

Wire-thin probes inserted into the brains of living people show the parts played by individual neurons.

Quantifying the ‘complexity’ of consciousness can tell us how rich our experiences are.

Developing predictive mechanistic models in biology is challenging. Elektrum uses neural architecture search, kinetic models and transfer learning to discover CRISPR–Cas9 cleavage kinetics, achieving high performance and biophysical interpretability.

The idea that consciousness requires a self has been around since at least Descartes. But problems of infinite regress, neuroscientific studies, and psychedelic experiences point to a different reality. ‘You’ may not be what you seem to be, writes James Cooke.

We typically feel like we are the conscious subject, the one who has experiences. Look around you in this moment and direct your attention to different objects. It can feel like we exist in our heads, behind our eyes, directing a spotlight of attention in order to wilfully make things conscious. This intuitive model of the mind has often been imported into the science and philosophy of consciousness, leading to confusion in our understanding of the true nature of experience. This subject is not the bodily organism, it is something that is felt to live inside us, the possessor of the body, the “you” that is reading these words now. Consciousness is very much a property of the bodily subject, but not of the conscious subject that is felt to live in our heads.

Thinking in terms of conscious subjects was present at the very origins of the scientific method, in the work of Rene Descartes saw the natural world as unconscious mechanism. Humans alone were conceived of as being conscious by virtue of a transcendent subject that could illuminate our experience of the world [1]. If we want to understand consciousness, however, postulating the existence of an inherently conscious subject merely passes the buck of explanation. What makes that conscious subject conscious? If it is intrinsically conscious then consciousness has not been explained. If not, then what makes it conscious, another subject within it? With this logic we end up in an infinite regress, with consciousness never being explained. This view of the mind has been dubbed the Cartesian Theatre by philosopher Daniel Dennett [2].

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Researchers at the MRC Weatherall Institute of Molecular Medicine’s Laboratory of Gene Regulation, led by Professor Doug Higgs and Dr. Mira Kassouf, have published a study in the journal Cell, in which they reveal another piece of the puzzle of how the code in our DNA is read.

In this study, the authors introduce the concept of “facilitators,” a newly identified type of non-coding DNA that can help to drive gene expression.

All of the cells in your body contain the same DNA. However, these cells are able to develop into over 200 different types and make up a variety of different specialized tissues such as the skin, the blood, and the brain.

Aging typically affects the brain and a person’s cognition.

Japanese horseradish, or wasabi as it is more widely known, may help improve certain areas of cognitive function in older adults, a new study suggests.

A neuromorphic supercomputer called DeepSouth will be capable of 228 trillion synaptic operations per second, which is on par with the estimated number of operations in the human brain.

By James Woodford

There is no computer even remotely as powerful and complex as the human brain. The lumps of tissue ensconced in our skulls can process information at quantities and speeds that computing technology can barely touch.

Key to the brain’s success is the neuron’s efficiency in serving as both a processor and memory device, in contrast to the physically separated units in most modern computing devices.

There have been many attempts to make computing more brain-like, but a new effort takes it all a step further – by integrating real, actual, human brain tissue with electronics.