Lifeboat Foundation

A Birmingham researcher has developed a new high-throughput device that produces libraries of nanomaterials using sustainable mechanochemical approaches.

Dr. Jason Stafford from the University’s School of Engineering invented the platform to create highly controllable reaction conditions and reduce the substantial amount of time researchers spend generating materials in the laboratory.

The benchtop device is a fully automated unit that can be programmed for parallel synthesis to produce a series of novel materials made in subtly different ways, so creating a library of advanced materials or product formulations for further testing and optimization.

As a greenhouse gas, carbon dioxide (CO₂) contributes to climate change as it accumulates in the atmosphere. One way to reduce the amount of unwanted CO₂ in the atmosphere is to convert the gas into a useful carbon product that can be used to generate valuable compounds.

An international team, led by researchers from Australia, have developed a system using nanotechnology that could allow people with diabetes to take oral insulin in the future. The researchers say the new insulin could be eaten by taking a tablet or even embedded within a piece of chocolate.

Researchers at AMOLF, working alongside colleagues from Germany, Switzerland, and Austria, have realized a new type of metamaterial through which sound waves flow in an unprecedented fashion. It provides a novel form of amplification of mechanical vibrations, which has the potential to improve sensor technology and information processing devices.

This metamaterial is the first instance of a so-called ‘bosonic Kitaev chain’, which gets its special properties from its nature as a topological material. It was realized by making nanomechanical resonators interact with laser light through radiation pressure forces. The discovery, which is published on March 27 in the renowned scientific journal Nature, was achieved in an international collaboration between AMOLF, the Max Planck Institute for the Science of Light, the University of Basel, ETH Zurich, and the University of Vienna.

The ‘Kitaev chain’ is a theoretical model that describes the physics of electrons in a superconducting material, specifically a nanowire. The model is famous for predicting the existence of special excitations at the ends of such a nanowire: Majorana zero modes. These have gained intense interest because of their possible use in quantum computers.

In a new paper published on May 1 in the journal Science Advances, researchers at Columbia Engineering used commercially available tabletop lasers to create tiny, atomically sharp nanostructures, or nanopatterns, in samples of a layered 2D material called hexagonal boron nitride (hBN).

A Virginia 14-year-old won $25,000 and earned the title of America’s Top Young Scientist this past fall for developing an affordable soap that can treat skin cancer. Heman Bekele plans to refine his invention over the next five years and create a nonprofit to distribute it in low-income communities.

The ninth grader spent four months competing against nine other finalists in 3M and Discovery Education’s Young Scientist Challenge, which encourages kids to “think creatively and apply the power of STEM to discover real-world solutions.” He was paired with a mentor, who helped him turn his idea into a prototype. It works by delivering cancer-fighting agents to the skin by way of lipid nanoparticles.

Bekele told NPR that he’s “always been really passionate about science and how things work,” and his experience growing up in Ethiopia inspired him to develop his soap.

A new peptide-carrying magnetic nanoparticle described in Science Advances has resolved both biological and behavioral symptoms in mouse models of Alzheimer’s disease.

A short peptide disassembles stable pathogenic tau fibrils of Alzheimer’s disease.

Ohh nice! New vaccine science it seems though I’m not familiar with vaccines, this does seem like a novel approach. It’s kinda future proof to train the immune system to target proteins that are shared across all coronavirus’ I’m hoping it provides, as do they, that it provides a better solution than current vaccines.

The vaccine is made by attaching harmless proteins from different coronaviruses to minuscule nanoparticles that are then injected to prime the body’s defences to fight the viruses should they ever invade.

Because the vaccine trains the immune system to target proteins that are shared across many different types of coronavirus, the protection it induces is extremely broad, making it effective against known and unknown viruses in the same family.

Continue reading “Scientists create vaccine with potential to protect against future coronaviruses” »

Excellent paper wherein Shen et al.

Abstract. Long single-stranded DNA (ssDNA) is a versatile molecular reagent with applications including RNA-guided genome engineering and DNA nanotechnology, yet its production is typically resource-intensive. We introduce a novel method utilizing an engineered Escherichia coli ‘helper’ strain and phagemid system that simplifies long ssDNA generation to a straightforward transformation and purification procedure. Our method obviates the need for helper plasmids and their associated contamination by integrating M13mp18 genes directly into the E. coli chromosome. We achieved ssDNA lengths ranging from 504 to 20 724 nt with titers up to 250 μg/l following alkaline lysis purification. The efficacy of our system was confirmed through its application in primary T-cell genome modifications and DNA origami folding. The reliability, scalability and ease of our approach promise to unlock new experimental applications requiring large quantities of long ssDNA.