Lifeboat Foundation

Researchers have determined a new feature of how the natural ends of our chromosomes are protected from harmful outcomes.

In a new study, University of Michigan researchers looked at how the DNA damage recognition process seems to know the difference between harmful DNA breaks that need repair versus the natural ends of chromosomes, called telomeres, that need to be left alone.

“If possible, you repair it, and if you can’t repair it, then the cell dies. You don’t want to keep dividing with broken DNA. That’s what happens in a normal cell, and that’s a good thing,” said Jayakrishnan Nandakumar, a professor of molecular, cellular and developmental biology.

Researchers publishing in Biogerontology have tested multiple biomarkers in an effort to use them as proxies for aging, and some of their findings were surprising. A simple study with direct […].

What if “looking your age” refers not to your face, but to your chest? Osaka Metropolitan University scientists have developed an advanced artificial intelligence (AI) model that utilizes chest radiographs to accurately estimate a patient’s chronological age. More importantly, when there is a disparity, it can signal a correlation with chronic disease.

These findings mark a leap in medical imaging, paving the way for improved early disease detection and intervention. The results are published in The Lancet Healthy Longevity.

The research team, led by graduate student Yasuhito Mitsuyama and Dr. Daiju Ueda from the Department of Diagnostic and Interventional Radiology at the Graduate School of Medicine, Osaka Metropolitan University, first constructed a deep learning-based AI model to estimate age from chest radiographs of healthy individuals.

Stem cells have been used to produce organoids that release the proteins responsible for forming dental enamel, a substance that shields teeth from harm and decay. This initiative was led by a multi-disciplinary team of researchers from the University of Washington in Seattle.

“This is a critical first step to our long-term goal to develop stem cell-based treatments to repair damaged teeth and regenerate those that are lost,” said Hai Zhang, professor of restorative dentistry at the UW School of Dentistry and one of the co – authors of the paper describing the research.

The findings are published today in the journal Developmental Cell. Ammar Alghadeer, a graduate student in Hannele Ruohola-Baker’s laboratory in the Department of Biochemistry at the UW School of Medicine was the lead author on the paper. The lab is affiliated with the UW Medicine Institute for Stem Cell and Regenerative Medicine.

23RD – 24TH AUGUST 2023 IN SOUTH AFRICA INTERNATIONAL LONGEVITY SUMMIT 23RD – 24TH AUGUST 2023 IN SOUTH AFRICA INTERNATIONALLONGEVITY SUMMIT REGISTER CALL FOR PAPERS REGISTER CALL FOR PAPERS JOIN THE EVENT WHY ATTEND THE CONFERENCE The International Longevity Summit in the most exclusive Conference for Longevity and Biotech revolution in Africa leveraging the dynamics […].

Scientist, longevity expert and biotechnology patent holder Raj Agni (aka Steven Schorr) beams in to discuss age deceleration, telomere extension and revolutionary plant-based anti-aging supplements on episode 114 of the Far Out with Faust podcast.

Raj Agni, also known as Steven M. Schorr, is a metaphysician, author, inventor, healer, alchemist, artist, musician, entrepreneur, and creator of Extended Longevity products designed to rebuild your telomeres. His clinics have operated for 14 years on Maui, Hawaii and he has treated over twenty thousand people.

Continue reading “Scientific Proof We Can Reverse Aging | Raj Agni Podcast” »

Watch the full episode and view show notes here: https://bit.ly/3Oo9mE5
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In this “Ask Me Anything” (AMA) episode, Peter delves into the realm of genetics, unraveling its connection to disease and emphasizing the value of understanding one’s genetic risks. He elucidates essential background knowledge on genetics before delving into the myriad reasons why individuals might consider genetic testing. Peter differentiates scenarios where genetic testing provides genuine insights from those where it may not be as useful. From there, Peter explores a comprehensive comparison of commercial direct-to-consumer genetic tests, providing insights on interpreting results and identifying the standout options for gaining insights into personal health.

Continue reading “Genetics: how they impact disease risk, what you can do about it, testing & more [AMA 50 sneak peek]” »

The Greenland shark is the poster child for animals with extreme longevity – and with good reason. As the longest-living vertebrates on Earth, they develop incredibly slowly in their frosty Arctic home, but when it comes to the longest-living animals on Earth, they’re not all that.

The ocean quahog is a pretty unremarkable-looking clam, reaching around 5 centimeters (2 inches) in size, and yet it can take them over 200 years to get there. The oldest on record was 507 years old, topping the Greenland shark, and yet it still only makes it the oldest known non-colonial animal.

“Animals living longer than 500 years?!” I hear you cry? Yes siree Bob. Let’s take a look at some of Earth’s oldest animals.

The Longevity Summit Dublin is dedicated to the recognition of emerging research developments aimed at extending the human healthspan. This much-anticipated event brings together leading scientists from around the world, fostering collaboration and knowledge exchange in pursuit of this critical objective.

The summit serves as a premier platform for showcasing the latest research and innovations within the longevity industry. Notably, keynote presentations by esteemed experts in the aging field provide valuable insights into the advancements being made towards enhancing overall well-being and extending lifespans.

Longevity. Technology: Scheduled to take place from the 17th to the 20th of August 2023, the Longevity Summit Dublin boasts a remarkable lineup of over 40 pioneering scientists, researchers and executives, as well as high net-worth investors – all of the attendees share a common focus on addressing the challenges posed by chronic diseases.