Lifeboat Foundation

By treating one of the root causes of aging – senescent cells – a new class of drugs, known as senolytics, has the potential to treat a wide range of age-related diseases rather than the traditional approach of dealing with them one at a time.

Today we are going to take a look at what senescent cells are, how they contribute to age-related diseases and a new review by the Mayo Clinic that shows what we can do about this problem. We all age, but the research suggests that we may not have to suffer from age-related ill health.

A great initiative by Laura Katrin Weston one of our amazing volunteers. She is supporting research fundraising using the wonderful artwork she produces at Black Cat Studios.

Black Cat Studios is a small private recording, music production and art studio in Leicestershire, UK, providing a range of services for musicians, broadcasters, and game developers. It is really great to see the community starting to use their talents and passions outside of longevity to help support research. All proceeds will go to Lifespan.io and we will use them to support cutting-edge medical research projects such as MouseAge.

Laura will be producing artwork based on 31 themes all with a longevity or transhumanist flavor to them based on this list:

Leading women’s magazine Marie Claire has a feature story on life extension out this month (approx 1.5 million circulation):

Forget about life after death. More and more, women around the country are seeking another kind of miracle: not dying at all.

What if you could hit the pause button on aging? Live to 120 without feeling a day over 80? More radical still, what if you could cheat death? Would you do it?

Continue reading “Meet the Extensionists: People Who Believe Immortality Is Possible” »

To coincide with our initiatives for Longevity Month, we are happy to announce some exciting updates for the MouseAge campaign to create a visual biomarker for mouse aging and speed the pace of longevity-focused mouse trials.

This year we want to continue this tradition by doing something special, making a video to showcase you, our community, as it is only with your outstanding help that we have been able to accomplish so much in such a short period of time.

To learn more visit our website today: https://www.leafscience.org/longevity-month-2017-tell-us-your-story/

A study by a team from the Houston Methodist Research Institute showed the potential of a treatment that targets telomeres in chromosomes to reverse cellular aging.

Randal Koene is recruiting top neuroscientists to help him make humans live forever.

This report on the NAD booster nicotinamide mononucleotide (NMN) will definetly be of interest to Lifeboat members.

NAD is the fountain of youth in mice and is boosted by NMN. This report includes highlights of Aug 2017 interview with Dr. David Sinclair, the researcher who discovered that the anti-aging molecule NAD has rejuvenating effects on mice.

Summary: NMN as a NAD-boosting anti-aging drug. Highlights of the August 2017 interview with David Sinclair, the scientist who discovered that the fountain of youth molecule NAD has remarkable rejuvenating effects on mice. The career of David Sinclair follows a link between sirtuins, resveratrol, NAD-boosting anti-aging compound nicotinamide mononucleotide (NMN), and calorie restriction.

Continue reading “Dr. David Sinclair, Discoverer of Anti-aging NAD Fad, Speaks About Human Trials of NMN” »

Dr. Mark Katakowski makes the case that rejuvenation of the bone marrow niche is a practical approach to life-extension today. Mark is President of the longevity company Forever Labs, and is a medical physicist with extensive experience developing stem cell therapies for neurological disease and injury.

Mark was first to demonstrate that microRNA functions as a communication molecule between brain tumor cells, a previously unknown mechanism of intercellular eukaryotic gene regulation. Based upon his use of stem cells to treat age-related disease, Mark surmises that rejuvenating the bone marrow provides significant opportunity to combat aging.