Lifeboat Foundation

New research from the University of Sussex holds promise for extending life expectancy and enhancing treatment options for a common and aggressive brain cancer affecting thousands in the UK annually and hundreds of thousands globally.

Published in the Journal of Advanced Science, the study revealed that the protein PANK4, previously overlooked, can hinder cancer cells’ response to chemotherapy in glioblastoma, an aggressive form of brain cancer and if the protein is removed, cancer cells respond better to the main chemotherapy drug used globally for the treatment of glioblastoma.

Continue reading “New research offers hope to those affected by aggressive brain cancer” »

This is all good but I really like the telomeres results.

Liz Parrish presents the stunning progress of gene therapies and how to collaborate to cure aging in this clip.

Continue reading “Living Longer, Living Better: Gene Therapy’s Stunning Progress For Longevity” »

A new study led by Stanford Medicine scientists demonstrates a simple way of studying organ aging by analyzing distinct proteins, or sets of them, in blood, enabling the prediction of individuals’ risk for diseases.

It is often thought that if we cure aging or find out how to upload a human mind that humans will be immortal. Today we will examine that notion and see how well it holds up against astronomical time lines.

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Continue reading “The Limits of Immortality & Digital Death” »

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The Schwartz Reisman Institute for Technology and Society and the Department of Computer Science at the University of Toronto, in collaboration with the Vector Institute for Artificial Intelligence and the Cosmic Future Initiative at the Faculty of Arts & Science, present Geoffrey Hinton on October 27, 2023, at the University of Toronto.

0:00:00 — 0:07:20 Opening remarks and introduction.
0:07:21 — 0:08:43 Overview.
0:08:44 — 0:20:08 Two different ways to do computation.
0:20:09 — 0:30:11 Do large language models really understand what they are saying?
0:30:12 — 0:49:50 The first neural net language model and how it works.
0:49:51 — 0:57:24 Will we be able to control super-intelligence once it surpasses our intelligence?
0:57:25 — 1:03:18 Does digital intelligence have subjective experience?
1:03:19 — 1:55:36 Q&A
1:55:37 — 1:58:37 Closing remarks.

Continue reading “Geoffrey Hinton | Will digital intelligence replace biological intelligence?” »

The aliens haven’t contacted us because they have uploaded themselves into digital information where they live forever anf create simulated universes that they live in or they upload themselves into femto tech level computational substrates and they could surround us.

Is Earth impossible? An exploration of the impossible earth hypothesis and its implications on science and existence.

Continue reading “Fermi Paradox: The Impossible Earth hypothesis” »

https://music.youtube.com/watch?v=n_LefGJgOJ8&si=UoInnL8Xy_wsXv_

Currently listening to this. He’s pretty decent, up there with Dr Daniel Amen in advancement/ideas. I barely started this episode but it seems AI can help in medicine and there’s more in this podcast concerning our personal health. This is some key issues for longevity.

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Continue reading “Shocking Truth About AI, Chronic Disease, Toxins, Diet & Lifestyle For Longevity | Eric Topol” »

The authors of a recent review published in Ageing Research Reviews summarize the research on epigenetic reprogramming and its potential as a rejuvenation therapy [1].

Aging leads to changes in the epigenome. Those changes can lead to alterations in gene regulation, affecting cellular homeostasis, and can play a role in age-associated phenotypes. Epigenetic modifications, the addition or removal of chemical groups to the DNA or DNA-associated proteins, have a profound impact on gene expression, tissue functions, and identity [2].

This review’s authors believe epigenetic reprogramming to be among the most currently promising interventions to stop or delay aging, potentially even reversing it at the cellular level. They believe that epigenetics are the basis of aging; therefore, being able to impact the epigenome would allow them to address multiple Hallmarks of Aging simultaneously.