Lifeboat Foundation

Published in Scientific Reports, this study is the first to provide evidence of new neuron formation—and the presence of stem cells—in the leopard gecko brain.

University of Guelph researchers have discovered the type of stem cell allowing geckos to create new brain cells, providing evidence that the lizards may also be able to regenerate parts of the brain after injury.

This finding could help in replacing human brain cells lost or damaged due to injury, aging or disease.

Continue reading “Study finds evidence that leopard geckos can make new brain cells” »

Can technology help us achieve near-everlasting life?

Entrepreneurs in Silicon Valley and beyond are attempting to disrupt what has long been seen as one of the only inevitabilities of life: death.

Computer scientists and artificial intelligence specialists are developing programs that allow people to theoretically avoid death, opening the door to near-everlasting life as well as a myriad of ethical and philosophical questions.

Continue reading “Disrupting death: Tech’s next big thing is immortality” »

August 17th sees our friends at UC Berkeley hosting an aging research summit which is shaping up to be pretty interesting.

Please join us for a day of speakers, awards, poster sessions, and valuable networking focused on cutting-edge aging research and technologies. Our aim is no less than to reimagine aging and elder care. A percentage of the proceeds from this event will support scholarships for students interested in research on aging & elder care…

It’s almost the weekend and what better way to celebrate than a nice long interview with one of the Heroes of aging research? Today we bring you a mega-interview with Dr. Aubrey de Grey.

Today we have an interview with Dr. Aubrey de Grey from the SENS Research Foundation. This interview conducted by Yuri Deigin was originally published in Russian language and he has kindly translated it into English so our audience can enjoy it too.

Yuri: Aubrey, thank you very much for agreeing to this interview. Why don’t we dive right in? I am sure everybody asks you this: how and when did you become interested in aging, and when did you decide to make it your life’s mission to defeat it?

Continue reading “Dr. Aubrey de Grey – SENS Research Foundation” »

A new way of administering drugs for wet age-related macular degeneration might be close.

Two studies by researchers at the University of Birmingham have shown that delivering drugs against the wet form of age-related macular degeneration (AMD) in the form of eyedrops might soon be possible in humans [1, 2].

What is age-related macular degeneration?

Continue reading “Wet AMD Drugs Might Soon Be Self-Administered” »

Dr Ian Pearson warns ‘electronic immortality’ will require careful planning. It could mean we live on after death in an ‘upgraded body’ — but could also mean we no longer own our own minds.

A new study shows that mice reprogram their gut tissues to repair injury rolling them from an aged state back to a more fetal-like one.

Getting old is one thing; getting old in a healthy way is another. Many elderly people suffer from all kinds of diseases and disorders, ranging from cardiovascular problems and diabetes to Alzheimer’s and Parkinson’s disease. Wouldn’t it be nice if we could keep the body young as we grow older to prevent disease associated with old age? For instance, would it be possible to slow down or reverse the aging processes in the cells of our body?

This question has gained a lot of interest from scientists, and their research has led to the discovery of the important role that the shortening of telomeres, the protective caps on our DNA, plays in aging. While this has been described in recent posts on the LEAF blog, I would like to address another mechanism that has seen an interesting leap forward, more or less by accident: rejuvenation of tissue.

Continue reading “Mice Reprogram Gut Tissue to a Fetal State to Heal Injury” »

Who wants to live forever? Thanks to these scientific breakthroughs, increased lifespans and reverse aging could be possible.

Aging may seem like the most natural—and inevitable—thing in life. Yet according to a new study in Nature Medicine, rejuvenating an aging body may be as easy as kitchen renovations. Simply swap drill and hammer for a cocktail of two drugs already on the market; rather than pulling out decrepit cabinets, kill off aged “zombie” cells.

These so-called senescent cells are a curious oddity: they’re frail, beat-up, and unable to perform their usual roles. Yet they simply refuse to die. What’s more, zombie cells actively leak inflammatory chemicals into their surroundings, damaging nearby tissue and—in a sense—“spreading” the negative effects of aging.

Yet because they’re extremely rare, amounting to only eight percent of the body’s cells at most, scientists have long wondered just how much they contribute to the aging process.

Continue reading “This Drug Combo Extends Lifespan and Healthspan in Mice” »