Lifeboat Foundation

The past year or so has seen an energetic debate over whether or not new neurons are generated in the adult human brain, a process known as neurogenesis. This process is well known and well studied in mice, and thought to be very important in the resilience and maintenance of brain tissue. The human data has always been limited, however, due to the challenges inherent in working with brain tissue in living people, and it was assumed was that the mouse data was representative of the state of neurogenesis in other mammals. In this environment, the publication of a careful study that seemed to rule out the existence of neurogenesis in adult humans produced some upheaval, and spurred many other teams to assess the human brain with greater rigor than was previously the case.

So far, all of the following studies published so far do in fact show evidence of adult neurogenesis in humans. This is the better of the two outcomes, as the regenerative medicine community has based a great deal of work on the prospect of being able to upregulate neurogenesis in order to better repair injuries to the central nervous system, or partially reverse the decline of cognitive function in the aging brain. The study here is particularly reassuring, as it shows that even in very late life there are signs that new neurons are being generated in the brain.

LEAF President Keith Comito on the channel TYT talking about healthy life extension! smile

Stephen Valentine is the architect for Timeship is creating the Timeship Building with Stephen Valentine. Timeship researches life extension and the Timeship Building will be a life extension facility. Read more on Stephen Valentine.

Top-80 longevity influencers in california by aging analytics agency.

Anne Corwin Atul Butte, M.D., Ph.D. Aubrey de Grey William Faloon Bill Andrews Cynthia Kenyon David A. Kekich David Botstein Eric Topol Eric Verdin Gordon J Lithgow Gregory Fahy Jim Strole

Link to Report: https://www.aginganalytics.com/longevity-in-california

Continue reading “Aging Analytics Agency Photo 7” »

The researchers of a new publication take a look at the effects of obesity on aging and consider its impact in the context of the Hallmarks of Aging, a popular theory that breaks down aging into nine distinct processes.

The case for obesity accelerating aging

Being overweight and carrying excessive amounts of visceral fat, a type of body fat that is stored in the abdominal cavity and surrounds a number of important internal organs, such as the liver, pancreas, and intestines, is known to increase the risk of age-related diseases.

Continue reading “Obesity Might Accelerate Aging” »

We are pleased to announce the launch of the Longevity Book Club hosted by LEAF Director Javier Noris, where you can join other longevity enthusiasts in reading the most interesting works that relate to our mission of ending age-related diseases.

You will also get the opportunity to listen to discussion panels and take part in Q&A sessions that are focused on books that touch on these important scientific, philosophical, moral and futuristic longevity topics. This is the ideal place to meet like-minded longevity enthusiasts who are working on building their knowledge on longevity and all of the implications that come with ending age-related diseases.

BioViva warmly welcomes Dr de Magalhaes to our Scientific Advisory Board!

Dr de Magalhaes graduated in Microbiology in 1999 from the Escola Superior de Biotecnologia in his hometown of Porto, Portugal, and then obtained his PhD in 2004 from the University of Namur in Belgium. Following a postdoc with genomics pioneer Prof George Church at Harvard Medical School, in 2008 Dr de Magalhaes was recruited to the University of Liverpool. He now leads the Integrative Genomics of Ageing Group (http://pcwww.liv.ac.uk/~aging/) which focuses on understanding the genetic, cellular, and molecular mechanisms of ageing. Dr de Magalhaes has authored over 100 publications and given over 100 invited talks, including three TEDx talks.

Ira Pastor, ideaXme longevity and aging Ambassador and Founder of Bioquark interviews Camillo Ricordi, Director Diabetes Research Institute University of Miami and Editor in Chief CellR4. They talk of the science behind the claim “We will cure diabetes!”.

Note: A decision was made to publish this interview despite the quality of the audio as it is still possible to understand the content. For links to research papers contact [email protected].

Continue reading “‘We will cure diabetes!’” »

Imagine a simple and effective treatment for restoring the sense of smell in people who have lost it or never had it in the first place – that could one day be possible as a result of early stage research on mice, in which olfactory nerves were replenished using stem cells.

Using droplets of globose basal cells – the same cells that naturally replace damaged and ageing neurons related to smell – scientists were able to get them to develop into full nerve cells, stretching right into the brain.

Ultimately a few squirts of stem cells were able to reconnect the axons leading to the olfactory signalling in the brains of the mice. Scientists are still a long way from repeating the trick with human beings, but it’s a very promising start.

Continue reading “Spraying Stem Cells Up The Noses of Mice Has Restored Their Sense of Smell” »