Lifeboat Foundation

In this video Dr. Lustgarten introduces his N of 1 experiment and gives an overview of the processes that he follows. He also discusses why he thinks it is important to track your own markers and not just rely on published trials.

Dr. Michael Lustgarten is a scientist at the Tufts University Human Nutrition Research Center on Aging in Boston, Massachusetts. His research currently focuses on the role of the gut microbiome and serum metabolome on muscle mass and function in older adults.
In this series of interviews Dr Lustgarten shares his experience with his rigorous n of 1 experiment over the last 7 years and shows how we or anyone can conduct a similar trial by tracking food, exercise and sleep, measure results and derive relationships between them, with a goal of extending our healthspan.

Continue reading “N Of 1 Extend Lifespan Experiment: How To Start | Dr Michael Lustgarten Interview Series 3 Ep 1” »

A stem cell researcher who founded his startup with the psychedelic-loving German billionaire Christian Angermayer, Peyer believes that aging is a disease that humans can fight with pharmaceuticals. He plans to prove it first by identifying disorders and diseases that mimic aging, such as those that cause loss of muscle mass, and then partner with researchers studying medicines for said diseases.

A bold proposal: that by 2050, a 70-year-old will look and feel like they’re 50.

That’s the gamble that 35-year-old James Peyer is taking with this Cambrian Biopharma “longevity startup,” the Times of London reports.

Continue reading “Tech Bro Thinks He’s Close to Cheating Death” »

Sorry if re-post…

A team of researchers affiliated with a large number of institutions in Japan has developed a vaccine that tricks the immune system into removing senescent cells. In their paper published in the journal Nature Aging, the group describes their vaccine, how it works and how effective it was when given to test mice.

Prior research has shown that part of the aging process is the development of senescent cells —cells that outlive their usefulness but fail to die naturally. Instead, they produce chemicals that can lead to inflammation, aging and a host of other ailments. Prior research has shown that senescence occurs when cells stop dividing. Prior research has also shown that senescent cells can lead to tumor growth in some instances and tumor suppression in others. Senescence also plays a role in tissue repair, and its impacts on the body vary depending on factors such as overall health and age. It is suspected that senescence is related to telomere erosion, and in some cases, environmental factors that lead to cell damage. In this new effort, the researchers have developed a vaccine that creates antibodies that attach to senescent cells, marking them for removal by white blood cells.

Continue reading “A new vaccine that alters senescent cells in a way that pushes the immune system into removing them” »

Yesterday’s longevity AMA: michael lustgarten, phd.

Questionsabout yesterday’s video, and more…AMA!

Continue reading “AMA Live Stream #1” »

Contrary to what you may think, getting old is not inevitable. And by getting old, I mean the bad parts: weakened muscles, fading memory, aching joints … or perhaps a disease such as cancer or diabetes makes an unwelcome appearance.

James Peyer, 35, is out to prove that age is, instead, like polio or tuberculosis. Those and other infectious diseases once were the biggest killers, until we developed effective vaccines or treatments.

Why, asked Peyer, co-founder of the New York longevity start-up Cambrian Biopharma, should age be any different? “Of our 100,000-year-plus history as a species, it’s been for only about 75 years that these diseases of ageing have been the primary predators of humankind.” He added: “We are rapidly zeroing in on our biggest.

How regenerative medicine promises to slow, or even reverse cognitive decline.

Japanese researchers have demonstrated a vaccine to remove senescent cells in mice. These so-called ‘zombie cells’ are a key driver of the aging process.

Senescent cells refer to those that have stopped dividing but do not die. They damage nearby healthy cells by releasing chemicals that cause inflammation.

The team identified a protein found in senescent cells in humans and mice and created a peptide vaccine based on an amino acid that constitutes the protein.

The vaccine enables the body to create antibodies that attach themselves to senescent cells, which are removed by white blood cells that adhere to the antibodies.

Clip during an interview made by Nicholas Singh, Senior Product Manager at Novos Labs to Kris Verburgh, CSO and Co-Founder of Novos Lab.

The clip shows the answer made by Kris Verburgh to a question made by José Cordeiro, PhD, MBA, Vice-Chairman of Humanity Plus, about the prediction made by Ray Kurzweil on the availability of full body human biological rejuvenation by 2045.

Continue reading “Kris Verburgh — CSO of Novos Labs views on Longevity Escape Velocity (con S/T en Español)” »