Lifeboat Foundation

Sea urchins are remarkable organisms. They can quickly regrow damaged spines and feet. Some species also live to extraordinary old ages and—even more remarkably—do so with no signs of poor health, such as a decline in regenerative capacity or an increase in age-related mortality. These ocean Methuselahs even reproduce as if they were still youngsters.

MDI Biological Laboratory Associate Professor James A. Coffman, Ph.D., is studying the regenerative capacity of sea urchins in hopes that a deeper understanding of the process of regeneration, which governs the regeneration of aging tissues as well as lost or damaged body parts, will lead to a deeper understanding of the aging process in humans, with whom sea urchins share a close genetic relationship.

In a paper recently published in Aging Cell, a leading journal in the field of aging biology, with Andrea G. Bodnar, Ph.D., of the Bermuda Institute of Ocean Studies, the scientists shed new light on the aging process in sea urchins, raising the prospect that the physical decline that typically accompanies aging is not inevitable.

Continue reading “Is aging inevitable? Not necessarily for sea urchins” »

New method for precisely identifying and treating fractures.

You’ve injured your knee. A doctor straps a listening device to it, and the noises you hear coming out of it are cringe-worthy. “Crackle! Krglkrglkrgl! Snap!”

Continue reading “Acoustic engineering transcribes crackling knee sounds into moving graph” »

Another exampme of how precision works.

While pregnant with her first child, Rhea Birusingh started experiencing blurry vision that her OB-GYN dismissed as an expected pregnancy-related change, but three months later, she went to her ophthalmologist, who discovered an inoperable 2-centimeter benign brain tumor behind her right eye. Now, nearly four months later, Birusingh’s son is healthy and her vision is normal, thanks to a powerful, precise radiation treatment.

“When you’re a pathologist and your eyes are a money maker, you start to get a little bit worried,” Birusingh, 37, of Howey-in-the-Hills, Florida, told FoxNews.com.

Continue reading “Precision radiation helps ward off first-time mom’s brain tumor” »

Very promising. Wonder how effective it is with Prescription Med. Addictions.

A type of brain cell known as microglia plays a key role in reducing the effects of cocaine in the brain, according to a major study by a team from the Research Institute of the McGill University Health Centre (RI-MUHC) in Montreal.

The discovery, published in the journal Neuron, establishes for the first time that microglia can diminish the adverse changes to neural circuitry brought on by the chronic use of cocaine and has significant implications for developing an effective treatment for addiction.

Continue reading “Mechanism that reduces effect of cocaine on brain discovered” »

Ever dream of becoming a dentist? Or, have family members needing new dentures? Or, know that one person who would look good if they only had some teeth. This 3D Printer is your answer.

An undergraduate at New Jersey Institute of Technology made his own plastic braces using a 3D printer, $60 of materials, and a healthy dose of ingenuity — and they actually worked.

Amos Dudley had braces in middle school, but he didn’t wear a retainer like he was supposed to, so his teeth slowly shifted back.

Continue reading “This college student 3D printed his own plastic braces for $60 — and they actually fixed his teeth” »

This machine will save lives by transforming unhealthy lungs into healthy ones.

This box lets lungs live outside the body so they can be used for transplants.

CHARLOTTESVILLE, Va., May 17, 2016 — A gene that scientific dogma insists is inactive in adults actually plays a vital role in preventing the underlying cause of most heart attacks and strokes, researchers at the University of Virginia School of Medicine have determined. The discovery opens a new avenue for battling those deadly conditions, and it raises the tantalizing prospect that doctors could use the gene to prevent or delay at least some of the effects of aging.

“Finding a way to augment the expression of this gene in adult cells may have profound implications for promoting health and possibly reversing some of the detrimental effects with aging,” said researcher Gary K. Owens, PhD, director of UVA’s Robert M. Berne Cardiovascular Research Center.

Unexpected Protective Effect

EPA’s new rules on Carbon Nano Tubes.

On May 16, 2016, the U.S. Environmental Protection Agency (EPA) promulgated, through a direct final rule, significant new use rules (SNUR) for 55 chemical substances that were the subject of premanufacture notices (PMN), including functionalized carbon nanotubes (CNT) (generic). EPA states that it determined that any use of the functionalized CNTs without the use of impervious gloves, where there is potential for dermal exposure; manufacturing the PMN substance for use other than as a thin film for electronic device applications; manufacturing, processing, or using the PMN substance in a form other than a liquid; use of the PMN substance involving an application method that generates a mist, vapor, or aerosol except in a closed system; or any release of the PMN substance into surface waters or disposal other than by landfill or incineration may cause serious health effects or significant adverse environmental effects. EPA states that the following tests would help characterize the health and environmental effects of the PMN substance: “a fish early-life stage toxicity test (OPPTS Test Guideline 850.1400); a daphnid chronic toxicity test (OPPTS Test Guideline 850.1300); an algal toxicity test (OCSPP Test Guideline 850.4500); a 90-day inhalation toxicity test (OPPTS 870.3465) with additional testing parameters beyond those noted at CFR 870.3465, for using the 90-day subchronic protocol for nanomaterial assessment; a two-year inhalation bioassay (OPPTS Test Guideline 870.4200); and a surface charge by electrophoresis (for example, using ASTM E2865-12 or NCL Method PCC-2 — Measuring the Zeta Potential of Nanoparticles).” The SNUR requires persons who intend to manufacture, import, or process any of the 55 chemical substances for an activity that is designated as a significant new use by the direct final rule to notify EPA at least 90 days before commencing that activity. The direct final rule will be effective July 15, 2016. If EPA receives written adverse or critical comments, or notice of intent to submit adverse or critical comments, on one or more of the SNURs before June 15, 2016, EPA will withdraw the relevant sections of the direct final rule before its effective date.

©2016 Bergeson & Campbell, P.C.

Continue reading “EPA Promulgates Significant New Use Rules for Functionalized Carbon Nano Tubes (Generic)” »

Interesting read on PTSD. Wonder how much this plays into DARPA’s own research around memory removal on PTSD patients. hmmm.

New research suggests that PTSD patients with a larger region of the brain that helps distinguish between safety and threat are more likely to respond to exposure-based therapy.

The study expands upon prior research that discovered having a smaller hippocampus is associated with increased risk of PTSD.

Continue reading “Size of Brain Region May Impact How Well Exposure Therapy Works for PTSD” »