Lifeboat Foundation

The historical context in which Brain Computer Interfaces (BCI) has emerged has been addressed in a previous article called “To Interface the Future: Interacting More Intimately with Information” (Kraemer, 2011). This review addresses the methods that have formed current BCI knowledge, the directions in which it is heading and the emerging risks and benefits from it. Why neural stem cells can help establish better BCI integration is also addressed as is the overall mapping of where various cognitive activities occur and how a future BCI could potentially provide direct input to the brain instead of only receive and process information from it.

EEG Origins of Thought Pattern Recognition
Early BCI work to study cognition and memory involved implanting electrodes into rats’ hippocampus and recording its EEG patterns in very specific circumstances while exploring a track both when awake and sleeping (Foster & Wilson, 2006; Tran, 2012). Later some of these patterns are replayed by the rat in reverse chronological order indicating a retrieval of the memory both when awake and asleep (Foster & Wilson, 2006). Dr. John Chapin shows that the thoughts of movement can be written to a rat to then remotely control the rat (Birhard, 1999; Chapin, 2008).

A few human paraplegics have volunteered for somewhat similar electrode implants into their brains for an enhanced BrainGate2 hardware and software device to use as a primary data input device (UPI, 2012; Hochberg et al., 2012). Clinical trials of an implanted BCI are underway with BrainGate2 Neural Interface System (BrainGate, 2012; Tran, 2012). Currently, the integration of the electrodes into the brain or peripheral nervous system can be somewhat slow and incomplete (Grill et al., 2001). Nevertheless, research to optimize the electro-stimulation patterns and voltage levels in the electrodes, combining cell cultures and neurotrophic factors into the electrode and enhance “endogenous pattern generators” through rehabilitative exercises are likely to improve the integration closer to full functional restoration in prostheses (Grill et al., 2001) and improved functionality in other BCI as well.

When integrating neuro-chips to the peripheral nervous system for artificial limbs or even directly to the cerebral sensorimotor cortex as has been done for some military veterans, neural stem cells would likely help heal the damage to the site of the limb lost and speed up the rate at which the neuro-chip is integrated into the innervating tissue (Grill et al., 2001; Park, Teng, & Snyder, 2002). These neural stem cells are better known for their natural regenerative ability and it would also generate this benefit in re-establishing the effectiveness of the damaged original neural connections (Grill et al., 2001).

Neurochemistry and Neurotransmitters to be Mapped via Genomics
Cognition is electrochemical and thus the electrodes only tell part of the story. The chemicals are more clearly coded for by specific genes. Jaak Panksepp is breeding one line of rats that are particularly prone to joy and social interaction and another that tends towards sadness and a more solitary behavior (Tran, 2012). He asserts that emotions emerged from genetic causes (Panksepp, 1992; Tran, 2012) and plans to genome sequence members of both lines to then determine the genomic causes of or correlations between these core dispositions (Tran, 2012). Such causes are quite likely to apply to humans as similar or homologous genes in the human genome are likely to be present. Candidate chemicals like dopamine and serotonin may be confirmed genetically, new neurochemicals may be identified or both. It is a promising long-term study and large databases of human genomes accompanied by medical histories of each individual genome could result in similar discoveries. A private study of the medical and genomic records of the population of Iceland is underway and has in the last 1o years has made unique genetic diagnostic tests for increased risk of type 2 diabetes, breast cancer prostate cancer, glaucoma, high cholesterol/hypertension and atrial fibrillation and a personal genomic testing service for these genetic factors (deCODE, 2012; Weber, 2002). By breeding 2 lines of rats based on whether they display a joyful behavior or not, the lines of mice should likewise have uniquely different genetic markers in their respective populations (Tran, 2012).

fMRI and fNIRIS Studies to Map the Flow of Thoughts into a Connectome
Though EEG-based BCI have been effective in translating movement intentionality of the cerebral motor cortex for neuroprostheses or movement of a computer cursor or other directional or navigational device, it has not advanced the understanding of the underlying processes of other types or modes of cognition or experience (NPG, 2010; Wolpaw, 2010). The use of functional Magnetic Resonance Imaging (fMRI) machines, and functional Near-Infrared Spectroscopy (fNIRIS) and sometimes Positron Emission Tomography (PET) scans for literally deeper insights into the functioning of brain metabolism and thus neural activity has increased in order to determine the relationships or connections of regions of the brain now known collectively as the connectome (Wolpaw, 2010).

Dr. Read Montague explained broadly how his team had several fMRI centers around the world linked to each other across the Internet so that various economic games could be played and the regional specific brain activity of all the participant players of these games can be recorded in real time at each step of the game (Montague, 2012). In the publication on this fMRI experiment, it shows the interaction between baseline suspicion in the amygdala and the ongoing evaluation of the specific situation that may increase or degree that suspicion which occurred in the parahippocampal gyrus (Bhatt et al., 2012). Since the fMRI equipment is very large, immobile and expensive, it cannot be used in many situations (Solovey et al., 2012). To essentially substitute for the fMRI, the fNIRS was developed which can be worn on the head and is far more convenient than the traditional full body fMRI scanner that requires a sedentary or prone position to work (Solovey et al., 2012).

In a study of people multitasking on the computer with the fNIRIS head-mounted device called Brainput, the Brainput device worked with remotely controlled robots that would automatically modify the behavior of 2 remotely controlled robots when Brainput detected an information overload in the multitasking brains of the human navigating both of the robots simultaneously over several differently designed terrains (Solovey et al., 2012).

Writing Electromagnetic Information to the Brain?
These 2 examples of the Human Connectome Project lead by the National Institute of Health (NIH) in the US and also underway in other countries show how early the mapping of brain region interaction is for higher cognitive functions beyond sensory motor interactions. Nevertheless, one Canadian neurosurgeon has taken volunteers for an early example of writing some electromagnetic input into the human brain to induce paranormal kinds of subjective experience and has been doing so since 1987 (Cotton, 1996; Nickell, 2005; Persinger, 2012). Dr. Michael Persinger uses small electrical signals across the temporal lobes in an environment with partial audio-visual isolation to reduce neural distraction (Persinger, 2003). These microtesla magnetic fields especially when applied to the right hemisphere of the temporal lobes often induced a sense of an “other” presence generally described as supernatural in origin by the volunteers (Persinger, 2003). This early example shows how input can be received directly by the brain as well as recorded from it.

Higher Resolution Recording of Neural Data
Electrodes from EEGs and electromagnets from fMRI and fNIRIS still record or send data at the macro level of entire regions or areas of the brain. Work on intracellular recording such as the nanotube transistor allows for better understanding at the level of neurons (Gao et al., 2012). Of course, when introducing micro scale recording or transmitting equipment into the human brain, safety is a major issue. Some progress has been made in that an ingestible microchip called the Raisin has been made that can transmit information gathered during its voyage through the digestive system (Kessel, 2009). Dr. Robert Freitas has designed many nanoscale devices such as Respirocytes, Clottocytes and Microbivores to replace or augment red blood cells, platelets and phagocytes respectively that can in principle be fabricated and do appear to meet the miniaturization and propulsion requirements necessary to get into the bloodstream and arrive at the targeted system they are programmed to reach (Freitas, 1998; Freitas, 2000; Freitas, 2005; Freitas, 2006).

The primary obstacle is the tremendous gap between assembling at the microscopic level and the molecular level. Dr. Richard Feynman described the crux of this struggle to bridge the divide between atoms in his now famous talk given on December 29, 1959 called “There’s Plenty of Room at the Bottom” (Feynman, 1959). To encourage progress towards the ultimate goal of molecular manufacturing by enabling theoretical and experimental work, the Foresight Institute has awarded annual Feynman Prizes every year since 1997 for contribution in this field called nanotechnology (Foresight, 2012).

The Current State of the Art and Science of Brain Computer Interfaces
Many neuroscientists think that cellular or even atomic level resolution is probably necessary to understand and certainly to interface with the brain at the level of conceptual thought, memory storage and retrieval (Ptolemy, 2009; Koene, 2010) but at this early stage of the Human Connectome Project this evaluation is quite preliminary. The convergence of noninvasive brain scanning technology with implantable devices among volunteer patients supplemented with neural stem cells and neurotrophic factors to facilitate the melding of biological and artificial intelligence will allow for many medical benefits for paraplegics at first and later to others such as intelligence analysts, soldiers and civilians.

Some scientists and experts in Artificial Intelligence (AI) express the concern that AI software is on track to exceed human biological intelligence before the middle of the century such as Ben Goertzel, Ray Kurzweil, Kevin Warwick, Stephen Hawking, Nick Bostrom, Peter Diamandis, Dean Kamen and Hugo de Garis (Bostrom, 2009; de Garis, 2009, Ptolemy, 2009). The need for fully functioning BCIs that integrate the higher order conceptual thinking, memory recall and imagination into cybernetic environments gains ever more urgency if we consider the existential risk to the long-term survival of the human species or the eventual natural descendent of that species. This call for an intimate and fully integrated BCI then acts as a shield against the possible emergence of an AI independently of us as a life form and thus a possible rival and intellectually superior threat to the human heritage and dominance on this planet and its immediate solar system vicinity.

References

Bhatt MA, Lohrenz TM, Camerer CF, Montague PR. (2012). Distinct contributions of the amygdala and parahippocampal gyrus to suspicion in a repeated bargaining game. Proc. Nat’l Acad. Sci. USA, 109(22):8728–8733. Retrieved October 15, 2012, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365181/pdf/pnas.201200738.pdf.

Birhard, K. (1999). The science of haptics gets in touch with prosthetics. The Lancet, 354(9172), 52–52. Retrieved from http://search.proquest.com/docview/199023500

Continue reading “Mapping the Mind to Merge with Machines: Experimental Research Approaches to Brain Computer Interfaces (BCIs)” »

At first glance, one would consider the proposition of a base on Mercury, our Sun’s closest satellite, as ludicrous. With daytime temperatures reaching up to 700K — hot enough to melt lead — while the dark side of the planet experiences a temperature average of 110K — far colder than anywhere on Earth, combined with the lack of any substantial atmosphere, and being deep in the Sun’s gravitational potential well, conditions seem unfavorable.

First impressions can be misleading however, as it is well known that polar areas do not experience the extreme daily variation in temperature, with temperatures in a more habitable range (< 273 K (0 °C)) and it has been anticipated there may even be deposits of ice inside craters. http://nssdc.gsfc.nasa.gov/planetary/ice/ice_mercury.html

And is not just habitable temperature and ice-water in its polar regions that make Mercury an interesting candidate for an industrial base. There are a number of other factors making it more favourable than either a Looner or Martian base:

Mercury is the second densest planet in our solar system — being just slightly less dense than our Earth — and is rich in valuable resources, the highest concentrations of many valuable minerals of any surface in the Solar System, in highly concentrated ores. Also, being the closest planet to the Sun, Mercury has vast amounts of solar power available, and there are predictions that Mercury’s soil may contain large amounts of helium-3, which could become an important source of clean nuclear fusion energy on Earth and a driver for the future economy of the Solar System. Therefore it is a strong candidate for an industrial base.

Continue reading “The Unlikely Option? An Industrial Base on Planet Mercury” »

The shift that has happened in 40 years which mainly has to do with climate change. Forty years ago, I could say in the Whole Earth Catalog, “we are as gods, we might as well get good at it”. Photographs of earth from space had that god-like perspective.

What I’m saying now is we are as gods and have to get good at it. Necessity comes from climate change, potentially disastrous for civilization. The planet will be okay, life will be okay. We will lose vast quantities of species, probably lose the rain forests if the climate keeps heating up. So it’s a global issue, a global phenomenon. It doesn’t happen in just one area. The planetary perspective now is not just aesthetic. It’s not just perspective. It’s actually a world-sized problem that will take world sized solutions that involves forms of governance we don’t have yet. It involves technologies we are just glimpsing. It involves what ecologists call ecosystem engineering. Beavers do it, earthworms do it. They don’t usually do it at a planetary scale. We have to do it at a planetary scale. A lot of sentiments and aesthetics of the environmental movement stand in the way of that.

Continue reading “We are as Gods…” and watch the video interview

I have been meaning to read a book coming out soon called Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves. It’s written by Harvard biologist George Church and science writer Ed Regis. Church is doing stunning work on a number of fronts, from creating synthetic microbes to sequencing human genomes, so I definitely am interested in what he has to say. I don’t know how many other people will be, so I have no idea how well the book will do. But in a tour de force of biochemical publishing, he has created 70 billion copies. Instead of paper and ink, or pdf’s and pixels, he’s used DNA.

Much as pdf’s are built on a digital system of 1s and 0s, DNA is a string of nucleotides, which can be one of four different types. Church and his colleagues turned his whole book–including illustrations–into a 5.27 MB file–which they then translated into a sequence of DNA. They stored the DNA on a chip and then sequenced it to read the text. The book is broken up into little chunks of DNA, each of which has a portion of the book itself as well as an address to indicate where it should go. They recovered the book with only 10 wrong bits out of 5.27 million. Using standard DNA-copying methods, they duplicated the DNA into 70 billion copies.

Scientists have stored little pieces of information in DNA before, but Church’s book is about 1,000 times bigger. I doubt anyone would buy a DNA edition of Regenesis on Amazon, since they’d need some expensive equipment and a lot of time to translate it into a format our brains can comprehend. But the costs are crashing, and DNA is a far more stable medium than that hard drive on your desk that you’re waiting to die. In fact, Regenesis could endure for centuries in its genetic form. Perhaps librarians of the future will need to get a degree in biology…

Link to Church’s paper

Source

Technology is as Human Does
When one of the U.S. Air Force’s top future strategy guys starts dorking out on how we’ve gotta at least begin considering what to do when a progressively decaying yet apocalyptically belligerent sun begins BBQing the earth, attention is payed. See, none of the proposed solutions involve marinade or species-level acquiescence, they involve practical discussion on the necessity for super awesome technology on par with a Kardeshev Type II civilization (one that’s harnessed the energy of an entire solar system).

Because Not if, but WHEN the Earth Dies, What’s Next for Us?
Head over to Kurzweil AI and have a read of Lt. Col. Peter Garretson’s guest piece. There’s perpetuation of the species stuff, singularity stuff, transhumanism stuff, space stuff, Mind Children stuff, and plenty else to occupy those of us with borderline pathological tech obsessions.

[BILLION YEAR PLAN — KURZWEIL AI]
[U.S. AIR FORCE BLUE HORIZONS FUTURE STUFF PROJECT]

I do not regret voting for this President and I would and will do it again. However.……I am not happy about our space program. Not at all. One would think there would be more resistance concerning the privatization of space and the inferior launch vehicles being tested or proposed. Indeed there would be objections except for a great deception being perpetrated on a nation ignorant of the basic facts about space flight. The private space gang has dominated public discourse with very little answering criticism of their promises and plans.
This writer is very critical of the flexible path.

It is a path to nowhere.

Compared to the accomplishments of NASA’s glory days, there is little to recommend the players in the commercial crew game. The most fabulous is Space X, fielding a cheap rocket promising cheap lift. There is so little transparency concerning the true cost of their launches that one space-faring nation has called the bluff and stated SpaceX launch prices are impossible. The Falcon 9, contrary to stellar advertising, is a poor design in so many ways it is difficult to know where to begin the list. The engines are too small and too many, the kerosene propellant is inferior to hydrogen in the upper stage, and promising to reuse spent hardware verges on the ridiculous. Whenever the truth about the flexible path is revealed, the sycophants begin to wail and gnash their teeth.

The latest craze is the Falcon “heavy.” The space shuttle hardware lifted far more, though most of the lift was wasted on the orbiter. With 27 engines the faux heavy is a throwback to half a century ago when clusters of small engines were required due to nothing larger being available. The true heavy rocket of the last century had five engines and the number of Falcon engines it would take to match the Saturn V proves just how far the mighty have fallen.

Continue reading “Flexible Path Flim Flam revised” »

http://www.sciencedaily.com/releases/2012/09/120905134912.htm

It is a race against time- will this knowledge save us or destroy us? Genetic modification may eventually reverse aging and bring about a new age but it is more likely the end of the world is coming.

The Fermi Paradox informs us that intelligent life may not be intelligent enough to keep from destroying itself. Nothing will destroy us faster or more certainly than an engineered pathogen (except possibly an asteroid or comet impact). The only answer to this threat is an off world survival colony. Ceres would be perfect.

A secret agent travels to a secret underground desert base being used to develop space weapons to investigate a series of mysterious murders. The agent finds a secret transmitter was built into a supercomputer that controls the base and a stealth plane flying overhead is controlling the computer and causing the deaths. The agent does battle with two powerful robots in the climax of the story.

Gog is a great story worthy of a sci fi action epic today- and was originally made in 1954. Why can’t they just remake these movies word for word and scene for scene with as few changes as possible? The terrible job done on so many remade sci fi classics is really a mystery. How can such great special effects and actors be used to murder a perfect story that had already been told well once? Amazing.

In contrast to Gog we have the fairly recent movie Stealth released in 2005 that has talent, special effects, and probably the worst story ever conceived. An artificially intelligent fighter plane going off the reservation? The rip-off of HAL from 2001 is so ridiculous.

Fantastic Voyage (1966) was a not so good story that succeeded in spite of stretching suspension of disbelief beyond the limit. It was a great movie and might succeed today if instead of miniaturized and injected into a human body it was instead a submarine exploring a giant organism under the ice of a moon in the outer solar system. Just an idea.

Continue reading “Verne, Wells, and the Obvious Future Part 3” »

“The more anxiety one produces, the more the discussion there would be about how real and how possible actual existential threats are.”

John Hunt recently queried me on what steps I might take to form an organization to advocate for survival colonies and planetary defense. His comment on anxiety is quite succinct. In truth the landing on the moon was the product of fear- of the former Soviet Union’s lead in rocket technology. As we as a nation quelled that anxiety the budget for human space flight dwindled. But the fear of a nuclear winter continued to grow along with the size of our arsenals.

Interestingly, at the height of the cold war, evidence of yet another threat to human existence was uncovered in the Yucatan peninsula of Mexico in 1981; Chicxulub. But even before the dinosaur killer was discovered, perhaps the greatest threat of all to humanity was born in 1973 when Herb Boyer and Stanley Cohen created the first genetically modified organism. The money to answer both of these threats by going into space continues to be expended by the military industrial complex.

Mile wide rocks in space and microscopic organisms on earth are both threats to our existence, but the third and undoubtedly greatest threat is our own apathy. Why do we expend the tremendous resources of our race on everything BUT keeping it from going extinct?

Continue reading “Christian Astronomers” »