Lifeboat Foundation

Quantum computing is about to get more complex. Researchers have evidence that large molecules made of nickel and chromium can store and process information in the same way bytes do for digital computers. The researchers present algorithms proving it’s possible to use supramolecular chemistry to connect “qubits,” the basic units for quantum information processing, in Chem on November 10. This approach would generate several kinds of stable qubits that could be connected together into structures called “two-qubit gates.”

“We have shown that the chemistry is achievable for bringing together two-qubit gates,” says senior author Richard Winpenny, Head of the University of Manchester School of Chemistry. “The molecules can be made and the two-qubit gates assembled. The next step is to show that these two-qubit gates work.”

Scientists from the University of Basel have succeeded in organizing spherical compartments into clusters mimicking the way natural organelles would create complex structures. They managed to connect the synthetic compartments by creating bridges made of DNA between them. This represents an important step towards the realization of so-called molecular factories. The journal Nano Letters has published their results.

Within a cell there are specialized compartments called organelles, as for example nucleus, mitochondria, peroxisomes and vacuoles that are responsible for specific functions of the cell. Almost all sophisticated biological functions of cells are realized by self-organization, a process by which molecules adopt a defined arrangement based on their specific conformations and properties, without outside guidance.

Using self-organization of nano-objects into complex architectures is a major strategy to produce new materials with improved properties or functionalities in fields such as chemistry, electronics and technology. For example, this strategy has already been applied to create networks of inorganic solid nanoparticles. However, so far, these networks were not able to mimic sophisticated structures that have biological functions within the cells and thus have potential application in medicine or biology.

Bioprinting is becoming more sophisticated daily. Students from Munich, Germany, hacked an Ultimaker 2+ to 3D print biomaterials even more efficient. Without a doubt, the yearly iGEM challenge is one of the yearly highlights for students in the field of biology, biochemistry, and biotechnology.

In a great example of a low-cost research solution that could deliver big results, University of Michigan scientists have created a window for lithium-based batteries in order to film them as they charge and discharge.

The future of lithium-ion batteries is limited, says University of Michigan researcher Neil Dasgupta, because the chemistry cannot be pushed much further than it already has. Next-generation lithium cells will likely use lithium air and lithium sulfur chemistries. One of the big hurdles to be overcome in making these batteries practical is dendrites — tiny branch-like structures of lithium that form on the electrodes.

Continue reading “A peek into the future of lithium batteries” »

PCG-1α therapy shows promise in treating age-related decline.

It is always a good idea to look closely at the biochemistry involved in any potential Alzheimer’s disease therapy that shows promise in mouse models. There is perhaps more uncertainty for Alzheimer’s than most other age-related conditions when it comes to the degree to which the models are a useful representation of the disease state in humans — which might go some way towards explaining the promising failures that litter the field. In the research here, the authors are aiming to suppress a step in the generation of amyloid-β, one of the proteins that aggregates in growing amounts and is associated with brain cell death in Alzheimer’s disease. They achieve this goal using gene therapy to increase the level of PGC-1α, which in turn reduces the level of an enzyme involved in the production of amyloid-β. Interestingly, increased levels of PGC-1α have in the past been shown to produce modest life extension in mice, along with some of the beneficial effects to health associated with calorie restriction.

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Now, from the wild side.

Quantum Theory Proves Consciousness Moves To Another Universe After Death. There is an interesting new theory emerging from a scientist long familiar with physics, quantum mechanics and astrophysics. Biocentrism teaches that life and consciousness are fundamental to the universe. It is consciousness that creates the material universe, not the other way around. At least, the new thinking that has given birth to the new theory of biocentrism, which the professor, Dr. Robert Lanza, freely espouses. Lana has been voted the 3rd most important scientist alive by the NY Times. Lanza is an expert in regenerative medicine and scientific director of Advanced Cell Technology Company. Before he has been known for his extensive research which dealt with stem cells, he was also famous for several successful experiments on cloning endangered animal species. Biocentrism—is a concept proposed in 2007 by American doctor of medicine Robert Lanza, a scientist in the fields of regenerative medicine and biology, which sees biology as the central driving science in the universe, and an understanding of the other sciences as reliant on a deeper understanding of biology. Biocentrism states that life and biology are central to being, reality, and the cosmos—consciousness creates the universe rather than the other way around. It asserts that current theories of the physical world do not work, and can never be made to work, until they fully account for life and consciousness. While physics is considered fundamental to the study of the universe, and chemistry fundamental to the study of life, biocentrism claims that scientists will need to place biology before the other sciences to produce a theory of everything.

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In Brief.

• Jean-Pierre Sauvage, Sir Fraser Stoddart and Bernard Feringa will share the prize for their design and synthesis of the ‘world’s smallest machines.’
• The state of molecular machines today is at the same level as that of the electric motor in the 1830’

A trio of European scientists brought home the 2016 Nobel Prize in Chemistry. Jean-Pierre Sauvage, Sir J. Fraser Stoddart and Bernard L. Feringa were awarded 8 million Swedish krona for their work on molecular machines.

Continue reading “Nanomachines Score The 2016 Nobel Prize in Chemistry” »

Three pioneers in the development of nanomachines, made of moving molecules, were awarded the Nobel Prize in Chemistry on Wednesday.

Bernard Feringa was the first person to develop a molecular motor; in 1999 he got a molecular rotor blade to spin continually in the same direction. Using molecular motors, he has rotated a glass cylinder that is 10,000 times bigger than the motor and also designed a nanocar.

A tiny lift, artificial muscles and miniscule motors. The Nobel Prize in Chemistry 2016 is awarded to Jean-Pierre Sauvage, Sir J. Fraser Stoddart and Bernard L. Feringa for their design and production of molecular machines. They have developed molecules with controllable movements, which can perform a task when energy is added.

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