Lifeboat Foundation

RNA secondary structure is critical to RNA regulation and function. We report a new N3-kethoxal reagent that allows fast and reversible labeling of single-stranded guanine bases in live cells. This N3-kethoxal-based chemistry allows efficient RNA labeling under mild conditions and transcriptome-wide RNA secondary structure mapping. The authors designed a chemical probe, azido-kethoxal, to specifically label guanosine in single-strand RNAs in live cells that could be used to determine transcriptome-wide RNA secondary structures.

Edward Alexander Bouchet (September 15, 1852 – October 28, 1918) was an African American physicist and educator and was the first African-American to earn a Ph.D. from any American university, completing his dissertation in physics at Yale in 1876. While completing his studies, Bouchet was also the first African American to be inducted in to Phi Beta Kappa for his stellar academic performance in his undergraduate studies. Bouchet’s original research focused on geometrical optics, and he wrote a dissertation entitled “On Measuring Refractive Indices.”

Unfortunately, after completing his dissertation, Bouchet was unable to find a university teaching position after college, probably because of racial discrimination. Bouchet moved to Philadelphia in 1876 and took a position at the Philadelphia’s Institute for Colored Youth (now Cheyney University of Pennsylvania), where he taught physics and chemistry for the next 26 years. Bouchet spent the next several years in several different teaching positions around the country. In 1916, Bouchet returned home to New Haven in poor health, and died in 1918 at age 66.

Dr. Bouchet’s impact on physics still resonates today around the world. The American Physical Society (APS Physics) confers the Edward A. Bouchet Award on some of the nation’s outstanding physicists for their contribution to physics. The Edward Bouchet Abdus Salam Institute was founded in 1988 by the late Nobel Laureate, Professor Abdus Salam under the direction of the founding Chairman Charles S. Brown. In 2005, Yale and Howard University founded the Edward A. Bouchet Graduate Honor Society in his name.

Did product safety laws lead to the dumbing down of science toys?

“Users should not take ore samples out of their jars, for they tend to flake and crumble and you would run the risk of having radioactive ore spread out in your laboratory.” Such was the warning that came with the Gilbert U-238 Atomic Energy Lab, a 1950s science kit that included four small jars of actual uranium. Budding young nuclear scientists were encouraged to use the enclosed instruments to measure the samples’ radioactivity, observe radioactive decay, and even go prospecting for radioactive ores. Yes, the Gilbert company definitely intended for kids to try this at home. And so the company’s warning was couched not in terms of health risk but rather as bad scientific practice: Removing the ore from its jar would raise the background radiation, thereby invalidating your experimental results.

Continue reading “Fun—and Uranium—for the Whole Family in This 1950s Science Kit” »

Along with personal jetpacks for every man, woman, and child (sure, why not), levitation is one of those conveniences that sci-fi has long promised us but has yet to deliver, other than magnetically levitating trains. But at Argonne National Laboratory in Illinois, physicist Chris Benmore and his colleagues are levitating objects with an unlikely tool: sound. It’s called acoustic levitation, and after breaking your brain with what seems to be an optical illusion, it’s poised to deliver advances in pharmacology, chemistry more broadly, and even robotics.

A novel method relying on biochemistry could provide an unambiguous signal of life on other worlds.

Computational biology is the combined application of math, statistics and computer science to solve biology-based problems. Examples of biology problems are: genetics, evolution, cell biology, biochemistry. [1].

Author at The Secrets of the Universe, I am a Biology and Chemistry high school student from Poland. I love writing about conquest and research in space and future possibilities for Humanity and Astrophysics.

New research in pigs examines how sugar intake affects the brain’s reward circuits and finds that changes are noticeable after just 12 days.

The concept of universal physics is intriguing, as it enables researchers to relate physical phenomena in a variety of systems, irrespective of their varying characteristics and complexities. Ultracold atomic systems are often perceived as ideal platforms for exploring universal physics, owing to the precise control of experimental parameters (such as the interaction strength, temperature, density, quantum states, dimensionality, and the trapping potential) that might be harder to tune in more conventional systems. In fact, ultracold atomic systems have been used to better understand a myriad of complex physical behavior, including those topics in cosmology, particle, nuclear, molecular physics, and most notably, in condensed matter physics, where the complexities of many-body quantum phenomena are more difficult to investigate using more traditional approaches.

Understanding the applicability and the robustness of universal physics is thus of great interest. Researchers at the National Institute of Standards and Technology (NIST) and the University of Colorado Boulder have carried out a study, recently featured in Physical Review Letters, aimed at testing the limits to universality in an ultracold system.

“Unlike in other physical systems, the beauty of ultracold systems is that at times we are able to scrap the importance of the periodic table and demonstrate the similar phenomenon with any chosen atomic species (be it potassium, rubidium, lithium, strontium, etc.),” Roman Chapurin, one of the researchers who carried out the study, told Phys.org. “Universal behavior is independent of the microscopic details. Understanding the limitations of universal phenomenon is of great interest.”