Caitlin Lewis
Caitlin Lewis is the Board Chair and Director of Project Pipeline and Strategy at the LEV Foundation.
Longevity Escape Velocity (LEV) Foundation exists to conduct and inspire research to proactively identify and address the most challenging obstacles on the path to the widespread availability of comprehensively effective treatments to prevent and reverse human age-related disease.
A primary focus of LEV Foundation’s work is to empirically demonstrate the feasibility and value of treating age-related disease — that is, the simultaneous deployment of therapies that independently address the distinct classes of damage that accumulate in aging bodies.
With a steadily increasing number of such therapies now showing benefits in both pre-clinical and clinical studies, there is a need to determine which combinations can already yield synergistic benefits in living organisms, starting with large-scale mouse lifespan studies of such therapeutic mixtures. Watch Less than halfway through our first Robust Mouse Rejuvenation study.
Read Robust Mouse Rejuvenation and Combining rejuvenation interventions in rodents: a milestone in biomedical gerontology whose time has come.
Caitlin was introduced to Aubrey de Grey and the longevity field in 2017 when she joined the SENS Research Foundation’s MitoSENS project as Research Associate to develop engineered therapeutic allotopic expression of mitochondrial genes for restoration of normal respiratory chain function.
In 2021, Caitlin began working with research leads at SRF on the strategic development of nascent projects, efforts which laid the foundation for her broader role at LEVF – evaluating areas of progress and stagnation across the entire longevity field, identifying neglected therapeutic targets, formulating novel interventions, and facilitating their development.
Caitlin earned her Bachelor’s Degree of Science in Molecular Biology from San Jose State University in 2016, with minors in chemistry and business. During her undergraduate career, she conducted research investigating the regulatory relationships between transcriptional co-activators and transcription factors common to developmental and oncogenic pathways. Caitlin is specifically interested in personalized medicine and targeted molecular therapeutics, and has joined SRF scientists with the goal of engineering improvements in human health.
Caitlin was chosen as one of 2000 Longevity Leaders by Longevity International and is a member of the Live Forever Club.
Cailtin is also in the Organizational Team for the Longevity Summit Dublin 2024.
Read Codon optimization is an essential parameter for the efficient allotopic expression of mtDNA genes, Successful Exogenous Expression of ATP8, a Mitochondrial Encoded Protein, From the Nucleus In Vivo, and The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics.
Visit her LinkedIn profile and ResearchGate.